Predictive value of the Ishii score for sarcopenia and the prognosis of older patients hospitalized with heart failure

Abstract

AimsAlthough sarcopenia is common and associated with poor outcomes in patients with heart failure, its simple screening methods remain unclear. We aimed to investigate the predictive value of the Ishii score, which includes age, grip strength, and calf circumference, for sarcopenia and its prognostic predictability in patients with heart failure.MethodsThis was a subanalysis of the FRAGILE‐HF study. Receiver operating characteristic curves were used to evaluate the predictive value for sarcopenia. Patients were stratified into the high and low Ishii score groups based on the cutoff values of the Ishii score determined by the Youden index for sarcopenia, and the 1‐year mortality rates were compared.ResultsOf the 1262 study participants, 936 were evaluated with sarcopenia, and 184 (55 women, 129 men) were diagnosed with sarcopenia. The areas under the receiver operating characteristic curves for sarcopenia were 0.73 and 0.87 for women and men, respectively. The optimal cutoff values for predicting sarcopenia were 165 and 141 for women and men, respectively. Using these cutoff values, the sensitivity and specificity for sarcopenia were 70.9% and 68.5% for women and 88.4% and 69.7% for men, respectively. At 1 year, 151 (low Ishii score group, 98; high Ishii score group, 53) deaths were observed. Adjusted Cox proportional hazards analysis showed that the high Ishii score group was significantly associated with 1‐year mortality.ConclusionAmong older patients hospitalized for heart failure, the Ishii score is useful for predicting sarcopenia and 1‐year mortality. Geriatr Gerontol Int 2023; ••: ••–••.

Comment on: Factors impacting early mobilization according to the Enhanced Recovery After Surgery Guideline following gastrointestinal surgery: A prospective study

“…We are grateful to Dr Bozkurt et al for their valuable comment on our paper. 1 In response to their concerns regarding our study, 2 we offer the following elucidation.…”

“…We appreciate the interest shown in our paper by Ates Bulut. 1,2 We offer the following responses. First, we would like to clarify that the numbers in Table 1 showing that gait speed measurements appeared similar between the two groups (deceased vs alive) is because the unit (m/s) and numbers are rounded to one decimal.…”