Predictive value of the neutrophil-to-lymphocyte ratio in patients with deep neck space infection secondary to acute bacterial tonsillitis

Bağlam, Tekin; Binnetoğlu, Adem; Yumuşakhuylu, Ali Cemal; Gerin, Fethullah; Demir, Berat; Sarı, Murat

doi:10.1016/j.ijporl.2015.06.016

Cited by 36 publications

(25 citation statements)

References 22 publications

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“…A cohort study examined the predictive value of NLR for radiologically-confirmed deep neck space infection (DNSI) in children (6 months-17 years) with bacterial tonsillitis. 46 Patients with uncomplicated bacterial tonsillitis ( n = 156) had a lower NLR than patients with DNSI ( n = 24; median NLR 1.5 vs 12.8, p < 0.01).…”

Section: Article In Pressmentioning

confidence: 90%

The utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: A systematic review and meta-analysis

Russell

Parajuli

Gale

et al. 2019

Journal of Infection

203

132

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Section: Article In Pressmentioning

confidence: 90%

The utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: A systematic review and meta-analysis

Russell

Parajuli

Gale

et al. 2019

Journal of Infection

203

132

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“…It has been used as inflammation marker in several diseases, such as myocardial infarction 20 , psoriasis 21 , gastritis 22 and gangrenous appendicitis 23 . Baglam 24 was the first to apply NLR as predictive factor for DNSIs, especially when occurring as a complication of acute bacterial tonsillitis in pediatric patients. An NLR cut-off of 5.4 was set to predict the risk of DNSI in these patients, with a sensitivity of 96% and a specificity of 83% (positive predictive value of 85% and negative predictive value of 95.4%).…”

Section: Discussionmentioning

confidence: 99%

New laboratory predictive tools in deep neck space infections

Fiorella

Greco

Madami

et al. 2020

Acta Otorhinolaryngol Ital

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SUMMARY Introduction Deep neck space infections (DNSIs) are a group of infective suppurative diseases involving deep neck spaces and cervical fascia. Necrotising and septic evolutions are rare, but severe complications can dramatically affect the prognosis and should be promptly managed. Clinical examination often has low sensitivity, although instrumental diagnosis may delay te treatment. We investigated two laboratory tools, LRINEC (Laboratory Risk Indicator for the Necrotizing fasciitis) and NLR (neutrophil to lymphocyte ratio), in the expectation to find a rapidly available predictive indicator that may help in distinguishing necrotising complications and/or systemic septic involvement. Methods A retrospective observational cohort study was performed on 118 patients who had underwent surgical treatment for DNSIs at our Surgical Unit. LRINEC, NLR and the product LRINEC x NLR were calculated. Results Statistical analysis showed that these scores may have utility in rapidly predicting the risk of necrotising fasciitis and systemic involvement at an early diagnostic stage. Conclusions Further studies with a larger cohort may be necessary in order to increase the sensitivity and specificity.

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“…Recently, several studies have also proved the prognostic value of NLR for systematic inflammatory diseases in pediatric settings. 20,21 Interestingly, some of these pediatric patients need to accepted immunotherapy targeting on CTLA-4 and programmed death (PD)-1 receptors, which is similar to post-transplant immunotherapy. 22,23 Thus, we can assume that LT patients may share similar immune-inflammatory backgrounds with some cancer patients, and NLR could be a reliable and accessible indicator to reflect it.…”

Section: Discussionmentioning

confidence: 99%

Baseline neutrophil‐lymphocyte ratio is associated with survival for infant living donor liver transplantation for biliary atresia

Meng

Guo

Wang

et al. 2020

Pediatric Transplantation

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Living donor liver transplantation (LDLT) in infants for congenital biliary atresia (BA) poses various challenges nowadays. We aim to investigate independent preoperative risk factors for LDLT in infants. We retrospectively analyzed medical records of infant patients who underwent LDLT surgery for BA from 1 July 2014 to 31 December 2016. Cox regression was used to explore risk factors. The Kaplan-Meier method was used to calculate the recipient and graft survival, and subgroup analysis was then applied according to the risk factors. Independent t test or Mann-Whitney U test was applied for comparison of certain factors between survival patients and death.A total of 345 infant LDLT for BA were included in the analysis. In the multivariate Cox-regression model, 3 factors were determined as independent risk factors for recipient and graft survival, there were neutrophil-lymphocyte ratio (NLR), pediat-

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Predictive value of the neutrophil-to-lymphocyte ratio in patients with deep neck space infection secondary to acute bacterial tonsillitis

Cited by 36 publications

References 22 publications

The utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: A systematic review and meta-analysis

The utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: A systematic review and meta-analysis

New laboratory predictive tools in deep neck space infections

Baseline neutrophil‐lymphocyte ratio is associated with survival for infant living donor liver transplantation for biliary atresia

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