Predictive value of the prognostic nutritional index for the severity of coronavirus disease 2019

Hu, Xiang; Deng, Huihui; Wang, Yuxia; Chen, Lingqiao; Gu, Xin; Wang, Xiaobo

doi:10.1016/j.nut.2020.111123

Cited by 55 publications

(59 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“… 32 Finally, eight observational studies, with a total of 2002 patients, were included. 8 , 16 , 17 , 33 , 34 , 35 , 36 , 37 However, one study did not report the adjusted OR of PNI as a continuous variable 33 and thus was not included in the meta‐analysis (Figure S1 ).…”

Section: Resultsmentioning

confidence: 99%

Clinical significance of prognostic nutrition index in hospitalized patients with COVID‐19: Results from single‐center experience with systematic review and meta‐analysis

et al. 2021

View full text Add to dashboard Cite

Background: We aimed to ascertain risk indicators of in-hospital mortality and severity as well as to provide a comprehensive systematic review and metaanalysis to investigate the prognostic significance of the prognostic nutrition index (PNI) as a predictor of adverse outcomes in hospitalized coronavirus disease 2019 (COVID-19) patients. Methods: In this cross-sectional study, we studied patients with COVID-19 who were referred to our hospital from February 16 to November 1, 2020. Patients with either a real-time reverse-transcriptase polymerase chain reaction test that was positive for COVID-19 or high clinical suspicion based on the World Health Organization (WHO) interim guidance were enrolled. A parallel systematic review/meta-analysis (in PubMed, Embase, and Web of Science) was performed. Results: A total of 504 hospitalized COVID-19 patients were included in this study, among which 101 (20.04%) patients died during hospitalization, and 372

show abstract

Section: Resultsmentioning

confidence: 99%

Clinical significance of prognostic nutrition index in hospitalized patients with COVID‐19: Results from single‐center experience with systematic review and meta‐analysis

et al. 2021

View full text Add to dashboard Cite

show abstract

“…It is therefore not surprising that malnutrition should be a common condition among older persons with COVID-19 [99]. Along these lines, if left untreated, it is also associated with a higher mortality [100], making the nutritional counseling especially important in older COVID-19 survivors [101]. This should not only include advice to increase calorie intake, but also to ensure adequate protein, vitamin, and mineral intakes [102].…”

Section: Covid-19-related Acute Sarcopeniatowards Prevention and Managementmentioning

confidence: 99%

Post-COVID-19 acute sarcopenia: physiopathology and management

et al. 2021

View full text Add to dashboard Cite

In this review, we discuss the pathophysiologic and management aspects of acute sarcopenia in relation to SARS-CoV-2 infection. COVID-19 is as a multi-organ infectious disease characterized by a severe inflammatory and highly catabolic status, influencing the deep changes in the body build, especially the amount, structure, and function of skeletal muscles which would amount to acutely developed sarcopenia. Acute sarcopenia may largely impact patients’ in-hospital prognosis as well as the vulnerability to the post-COVID-19 functional and physical deterioration. The individual outcome of the COVID-19 and the degree of muscle mass and functional loss may be influenced by multiple factors, including the patient’s general pre-infection medical and functional condition, especially in older adults. This paper gathers the information about how the SARS-CoV-2 hyper-inflammatory involvement exacerbates the immunosenescence process, enhances the endothelial damage, and due to mitochondrial dysfunction and autophagy, induces myofibrillar breakdown and muscle degradation. The aftermath of these acute and complex immunological SARS-CoV-2-related phenomena, augmented by anosmia, ageusia and altered microbiota may lead to decreased food intake and exacerbated catabolism. Moreover, the imposed physical inactivity, lock-down, quarantine or acute hospitalization with bedrest would intensify the acute sarcopenia process. All these deleterious mechanisms must be swiftly put to a check by a multidisciplinary approach including nutritional support, early physical as well cardio-pulmonary rehabilitation, and psychological support and cognitive training. The proposed holistic and early management of COVID-19 patients appears essential to minimize the disastrous functional outcomes of this disease and allow avoiding the long COVID-19 syndrome.

show abstract

“…Healthy nutrition is very important and anyway mistaken or unbalanced diet can be risk factor affecting development of virus pathogenesis. Several research groups have shown that malnutrition or obesity exacerbate COVID-19 disease [35][36][37][38][39]. Therefore, to increase immunity in case of SARS-CoV-2 infection, an optimal diet was recommended with the inclusion of all the necessary nutritional components, trace elements and vitamins [35,[39][40][41][42].…”

Section: Quantitate Evaluation Of Socioeconomic Factors and Progress Of Virus Infectionmentioning

confidence: 99%

Economic and social factors affecting the epidemiological process of the SARS-CoV-2 coronavirus

Пономаренко¹

2021

Preprint

View full text Add to dashboard Cite

Summary Aim. Analyze the impact of several economic and social factors on the course of the COVID-19 pandemic, comparing the latest statistics in large and representative samples. Assess the factors inhibiting the negative consequences of the infectious process of the SARS-CoV-2 virus. Materials and methods. To create this review, the required academic and media publications also statistical data were found on the Internet for the selected keywords, both for a single tag and in various combinations of them. Population statistics have been created on the base of data available on the Internet. Results and discussion. The relationship between economic or social factors and the impacts of the 15-month COVID-19 pandemic in different regions was investigated using a variety of available statistics for five continents and 53 countries. A positive relationship was found between the consequences of the SARS-CoV-2 epidemic and GDP per capita or the type of human diet with correlation coefficients in the range of 0.48-0.87. The development of the viral epidemic demonstrates a less clear correlation on population density from r = -0.68 to r = -0.16, depending on the selected group of countries. For island nations, geographic isolation was the dominant defense against SARS-CoV-2 infection. Conclusions. An analytical and quantitative study of economic or social aspects and numerous statistics on the spread of the COVID-19 pandemic, carried out on large representative samples, showed that, the productive infection and pathogenicity of SARS-CoV-2, critically increase with an excessive amount of consumed proteins and fats. To successfully control of the progression COVID-19 disease, the WHO guidelines for the amount of macronutrients consumed should be followed. This cost-effective approach will reduce health care expenditures in all countries during the epidemic.

show abstract

Predictive value of the prognostic nutritional index for the severity of coronavirus disease 2019

Cited by 55 publications

References 21 publications

Clinical significance of prognostic nutrition index in hospitalized patients with COVID‐19: Results from single‐center experience with systematic review and meta‐analysis

Clinical significance of prognostic nutrition index in hospitalized patients with COVID‐19: Results from single‐center experience with systematic review and meta‐analysis

Post-COVID-19 acute sarcopenia: physiopathology and management

Economic and social factors affecting the epidemiological process of the SARS-CoV-2 coronavirus

Contact Info

Product

Resources

About