Predictive Value of the Systolic Time Intervals in Primary Myocardial Disease

Lewis, Basil S.; Armstrong, T.G.; Everson, Raymond C.; Gotsman, Mervyn S.

doi:10.1378/chest.64.4.431

Cited by 9 publications

(5 citation statements)

References 24 publications

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“…All presented the strict criteria of myopathy (Weissler, Harris, andSchoenfeld, 1968, restrictive physiology (Fowler, 1971). None had obstruc-1969;Lewis et al, 1973). Therefore we have re-tive or purely congestive cardiomyopathy, in which the viewed our cases of these two disorders to see restrictive features may develop late in the course of the whether systolic intervals might provide a reliable disease.…”

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confidence: 83%

Usefulness of systolic time intervals in differential diagnosis of constrictive pericarditis and restrictive cardiomyopathy.

Khullar¹,

Lewis²

1976

Heart

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Systolic time intervals in 15 patients with constrictive pericarditis and seven patients with restrictive cardiomyopathy were compared in order to assess their value in the differential diagnosis of the two disorders. Clinical examination had failed to make the distinction. Right heart catheterization was helpful in diagnosing restriction but failed to differentiate patients with constrictive pericarditis from those with restrictive cardiomyopathy. The systolic time intervals clearly separated the two groups. The PEP/LVET was normal in all patients with constrictive pericarditis (0.34 +/- 0.01) and abnormal in all patients with restrictive cardiomyopathy (0.70 +/- 0.09, P less than 0.001). In 13 patients (five with restrictive cardiomyopathy and eight with constrictive pericarditis) the results of quantitative left ventricular angiocardiography were available. A high correlation (r=-0.90, P less than 0.01) between the PEP/LVET and the ejection fraction confirmed the validity of the PEP/LVET as a measure of left ventricular performance in these patients. Thus the systolic time intervals clearly distinguished between constrictive pericarditis and restrictive cardiomyopathy and are a reliable non-invasive technique for making the difficult differential diagnosis.

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confidence: 83%

Usefulness of systolic time intervals in differential diagnosis of constrictive pericarditis and restrictive cardiomyopathy.

Khullar¹,

Lewis²

1976

Heart

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“…[39][40][41] It is difficult to draw any conclusions from changes in PEP or ET alone; however, in humans, the ratio of PEP to ET is an accepted reflection of left ventricular performance. 42 A study 41 conducted in humans revealed a significant correlation between the ratio of PEP to ET and ejection fraction and a modest correlation with circumferential fiber shortening. Increases in ejection fraction and circumferential fiber shortening are associated with decreases in the ratio of PEP to ET; however, preload and afterload remain relatively constant.…”

mentioning

confidence: 99%

Comparison of the cardiopulmonary effects of anesthesia maintained by continuous infusion of romifidine, guaifenesin, and ketamine with anesthesia maintained by inhalation of halothane in horses

McMurphy¹,

Young²,

Marlin³

et al. 2002

ajvr

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“…Noninvasive techniques include the recording and measurement of the time intervals of the cardiac cycle (Weissler, Peeler, and Roehll, 1961;Weissler, Harris, and Schoenfeld, 1968;Kumar and Spodick, 1970;Lewis et al, 1973) and echocardiography (Feigenbaum, 1972;Fortuin, Hood, and Craige, 1972;McDonald, 1974). We have used the systolic time intervals and echocardiography to study myocardial performance in detail in a group of patients with chronic renal failure.…”

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confidence: 99%

Left ventricular function in chronic renal failure.

Lewis¹,

Milne²,

Goldberg³

1976

Heart

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Left ventricular function was studied in 14 patients with end-stage chronic renal failure using non-invasive methods (echocardiography and systolic time intervals). Patients were divided into 3 groups. Group 1 consisted of 5 patients who were normotensive at the time of study and group 2 of 7 patients who were hypertensive when studied. Group 3 consisted of 2 patients: one was recetving propranolol and the other, studied 302 days after renal transplantation, was receiving digitalis for recurrent episodes of cardiac failure.All except the patient receiving propranolol had normal left ventricular function in systole with norwal measurements offractional fibre shortening (% AS, EF) and normal measurements relating to the velocity of ventricular contraction (mean Vcf, mean velocity of posterior wall motion). Stroke volume and cardiac output were normal in some patients but were increased in patients with fluid overload. Early diastolic compliance of the left ventricle seemed to be normal except in the patient with recurrent cardiacfailure. The study provided no evidence for the existence of a specific uraemic cardiomyopathy.

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Predictive Value of the Systolic Time Intervals in Primary Myocardial Disease

Cited by 9 publications

References 24 publications

Usefulness of systolic time intervals in differential diagnosis of constrictive pericarditis and restrictive cardiomyopathy.

Usefulness of systolic time intervals in differential diagnosis of constrictive pericarditis and restrictive cardiomyopathy.

Comparison of the cardiopulmonary effects of anesthesia maintained by continuous infusion of romifidine, guaifenesin, and ketamine with anesthesia maintained by inhalation of halothane in horses

Left ventricular function in chronic renal failure.

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