2021
DOI: 10.1016/j.cegh.2021.100870
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Predictor for cardiovascular risk in patients with type-2 diabetes mellitus

Abstract: Thelimited information available concerning the role of periostin associated with cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Therefore, this study aimed to find out the association between periostin level and inflammatory markers in patients with T2DM as well as in the acute coronary syndrome (ACS) patients. Methods: This cross-sectional study randomly included a total of 210 participants, comprising T2DM (n = 130), ACS (n = 40), and healthy group (n = 40). All anthropometric measure… Show more

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Cited by 2 publications
(4 citation statements)
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“…It has been previously mentioned [31] that fatal coronary artery lesions exhibit a link between serum CRP and histology CRP staining. The results of this study are consistent with prior studies [32,33] in that they demonstrate a highly significant rise in CRP levels for both patient groups (G1 and G2) when compared to the C group. Determining the level of blood antioxidants and OS markers as a diagnostic and prognostic tool for the medical management of MI is essential given the imbalanced oxidative state and antioxidant activity in MI patients [34].…”
Section: Discussionsupporting
confidence: 91%
“…It has been previously mentioned [31] that fatal coronary artery lesions exhibit a link between serum CRP and histology CRP staining. The results of this study are consistent with prior studies [32,33] in that they demonstrate a highly significant rise in CRP levels for both patient groups (G1 and G2) when compared to the C group. Determining the level of blood antioxidants and OS markers as a diagnostic and prognostic tool for the medical management of MI is essential given the imbalanced oxidative state and antioxidant activity in MI patients [34].…”
Section: Discussionsupporting
confidence: 91%
“…Lastly, circulating Periostin has been proposed as a potential biomarker in some instances such as for cardiovascular risk, early cancer detection, or different type 2 inflammatory diseases [39][40][41][42] . Our own and other previous work suggests that reduced gene expression levels of Postn are reliable predictors of aging and associated metabolic disorders 22,43 .…”
Section: Discussionmentioning
confidence: 99%
“…Circulating Periostin has been proposed as biomarker of several inflammatory, chronic and metabolic diseases [39][40][41][42] , but its role in relation to aging in mice and humans is only now emerging 22,43 . To explore the link between aging and muscle dysfunction, we measured circulating human Periostin (hPOSTN) in serum samples from two separate human study cohorts 63,64 .…”
Section: Circulating Periostin May Predict Muscle Dysfunction In Geri...mentioning
confidence: 99%
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