Predictors for Incidence of Primary Open-Angle Glaucoma in a South Indian Population

Vijaya, Lingam; Asokan, Rashima; Panday, Manish; Choudhari, Nikhil S.; Ramesh, Shruthy Vaishali; Velumuri, Lokapavani; Boddupalli, Sachi Devi; Sunil, Govindan T.; George, Ronnie

doi:10.1016/j.ophtha.2014.01.014

Cited by 45 publications

(43 citation statements)

References 26 publications

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“…Among Asians, cross‐sectional studies in Chinese, Malay and Japanese populations consistently observed that diabetes was not associated with POAG, after adjusting for relevant confounders . Interestingly, prospective population‐based studies in European ancestry, African ancestry and Indian populations collectively showed that baseline diabetes was not associated with incident POAG . Taken together, the current findings seem to suggest an ethnic difference in the association of diabetes with POAG, where significant associations were reported in Western populations, but not in Asians.…”

Section: Introductionsupporting

confidence: 53%

“…reported in a Chinese population that individuals with hypertension were about 2.5 times as likely to have POAG . On the contrary, in a 6‐year follow‐up study among Indian adults (Chennai Eye Study), it was observed that baseline hypertension was protective for the development of POAG (odds ratio [OR] = 0.60), after adjusting for age, gender and habitation type . However, other cross‐sectional and prospective population‐based studies in African ancestry, European ancestry, Hispanic and Asian populations did not observe significant associations between hypertension and POAG …”

Section: Introductionmentioning

confidence: 96%

“…However, it should be noted that publication bias may be present in this meta‐analysis as most included studies for the meta‐analysis reported significant and positive direction associations between diabetes with POAG; on the other hand, studies, which previously reported nil associations, were not comprehensively included in that review (i.e. Beijing Eye Study, Barbados Eye Study, Chennai Eye Study and Kumejima Study) . Considering the sheer size of these inadvertently excluded studies, the direction and magnitude of pooled estimate might have been different should these studies were included in the meta‐analysis.…”

Section: Introductionmentioning

confidence: 99%

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Associations between chronic systemic diseases and primary open angle glaucoma: an epidemiological perspective

Tham

Cheng

2016

Clinical Exper Ophthalmology

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Glaucoma is a leading cause of global irreversible blindness. Primary open angle glaucoma (POAG) is the most common form of glaucoma and affects 44.1 million individuals worldwide. Elevation of intraocular pressure and impairment of vascular supply to the optic nerve head are two key pathogenic processes in the development of POAG. In this regard, chronic systemic conditions such as hypertension, diabetes and obesity have been postulated to be correlated with these two pathogenic processes. Thus, it is plausible that chronic systemic diseases may act as risk factors for POAG. The aim of this review is to summarize the current evidence on the associations of chronic systemic diseases with POAG. These information will help to further ascertain the risk factors for POAG and improve the early detection of POAG.

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Section: Introductionsupporting

confidence: 53%

Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

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Associations between chronic systemic diseases and primary open angle glaucoma: an epidemiological perspective

Tham

Cheng

2016

Clinical Exper Ophthalmology

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“…Myopia has been found to be a significant risk factor for glaucoma 21, 39, 40, 41, 42, 43, 44. That myopia is a risk factor for glaucoma and that it is also more prevalent among Asian patients may help explain increased prevalence 39 .…”

Section: Myopiamentioning

confidence: 98%

“…That myopia is a risk factor for glaucoma and that it is also more prevalent among Asian patients may help explain increased prevalence 39 . In addition, that high myopia 42 and increased axial length in certain age groups have both been identified as risk factors43, 44 suggests that the risk of glaucoma development and progression increases with the degree of myopia 44 …”

Section: Myopiamentioning

confidence: 99%

Glaucoma history and risk factors

McMonnies

2017

Journal of Optometry

309

193

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Apart from the risk of developing glaucoma there is also the risk that it is not detected and irreversible loss of vision ensues. Some studies of methods of glaucoma diagnosis have examined the results of instrument-based examinations with great if not complete reliance on objective findings in arriving at a diagnosis. The very valuable advances in glaucoma detection instrument technologies, and apparent increasing dependence on them, may have led to reduced consideration of information available from a patient history in those studies. Dependence on objective evidence of glaucomatous pathology may reduce the possibility of detecting glaucoma suspects or patients at risk for becoming glaucoma suspects. A valid positive family history of glaucoma is very valuable information. However, negative family histories can often be unreliable due to large numbers of glaucoma cases being undiagnosed. No evidence of family history is appropriate rather than no family history. In addition the unreliability of a negative family history is increased when patients with glaucoma fail to inform their family members. A finding of no family history can only be stated as no known family history. In examining the potential diagnostic contribution from a patient history, this review considers, age, frailty, race, type and degree of refractive error, systemic hyper- and hypotension, vasospasm, migraine, pigmentary dispersion syndrome, pseudoexfoliation syndrome, obstructive sleep apnea syndrome, diabetes, medication interactions and side effects, the degree of exposure to intraocular and intracranial pressure elevations and fluctuations, smoking, and symptoms in addition to genetics and family history of the disease.

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Risk Factors

Nouri‐Mahdavi¹

2016

Pearls of Glaucoma Management

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Predictors for Incidence of Primary Open-Angle Glaucoma in a South Indian Population

Cited by 45 publications

References 26 publications

Associations between chronic systemic diseases and primary open angle glaucoma: an epidemiological perspective

Associations between chronic systemic diseases and primary open angle glaucoma: an epidemiological perspective

Glaucoma history and risk factors

Risk Factors

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