Predictors of caregiver burden in aged caregivers of demented older patients

Tsai, Chia Fen; Hwang, Wei Shen; Lee, Jun Jun; Wang, Wen Fu; Huang, Ling Chun; Huang, Li; Lee, Wei Ju; Sung, Pi Shan; Liu, Yi Chien; Hsu, Chih Cheng; Fuh, Jong Ling

doi:10.1186/s12877-021-02007-1

Cited by 79 publications

(56 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another novelty of our study is the knowledge gained about the care of PSP and CBS patients during initial phases of the disease. Interestingly, we did not find significant correlations between burden of care and patient age, caregiver age or caregiver occupational status, which is in contradiction to other reports in the literature (Tsai et al 2021 ; Schneider et al 1999 ; Iavarone et al 2014 ). The correlations between educational level of the patient and close patient-caregiver relationship (partner or first-degree relative) with CB also need to be verified in future studies.…”

Section: Discussioncontrasting

confidence: 99%

Caregiver strain in progressive supranuclear palsy and corticobasal syndromes

et al. 2021

View full text Add to dashboard Cite

Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) progress relentlessly and lead to a need for care. Caregiving is often burdensome. Little is known about the course of caregiver burden (CB) in PSP and CBS patients. Longitudinal analysis of CB in family members caring for PSP and CBS patients. Single-center longitudinal pilot study in 68 newly diagnosed patients with probable PSP and CBS (52 Richardson’s syndrome; 1 progressive gait freezing of PSP; 15 CBS). Demographic, educational, occupational parameters, family status, motor functions (UPDRSIII, Hoehn and Yahr Score, Tinetti) and neuropsychological performance (CERAD Plus, Frontal Assessment Battery) were assessed, as well as behavioral and neuropsychiatric impairments (Frontal Behavioral Inventory, Neuropsychiatric Inventory), activities of daily living (ADL) and caregiver burden using the Caregiver Strain Index (CSI), in most patients also the Zarit Burden Interview (ZBI). Patients were followed up every 6 months for up to 2 years. Caregivers reported mild to moderate CB at baseline, which increased by 25–30% in 2 years and was significantly greater in PSP than in CBS. Risk for mental health problems increased over time, especially in female caregivers (depression). Important patient-related factors were apathy, aspontaneity, depression, irritability, disorganization, poor judgment, impairment of language, impairments in ADL, a high educational level of the patient and close family relationship. Behavioral symptoms and impaired ADL are the main patient-related factors of CB in PSP and CBS. CB can be severe and needs to be assessed repeatedly from the time of diagnosis to provide comprehensive support.

show abstract

Section: Discussioncontrasting

confidence: 99%

Caregiver strain in progressive supranuclear palsy and corticobasal syndromes

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Multiple regression analyses demonstrated that deficits in IADL were independently associated with all of the total, PS, and RS scores in ZBI after correcting various patient's conditions. The results agree with the relationship between caregiver burden and IADL reported in previous studies on dementia (21,26) including DLB (3,27). Multiple regression analyses also revealed that the "psychosis" factor was also associated with the total score in ZBI, and that the "affection" factor was independently associated with the total and PS scores in ZBI.…”

Section: Discussionsupporting

confidence: 90%

Impact of Behavioral and Psychological Symptoms on Caregiver Burden in Patients With Dementia With Lewy Bodies

et al. 2021

View full text Add to dashboard Cite

Background/Objective: Behavioral and psychological symptoms of dementia (BPSD) have been reported to affect caregiver burden in patients with dementia with Lewy bodies (DLB). However, the factor structure of BPSD and the factors that affect caregiver burden in DLB remain unknown. This study sought to classify BPSD and to reveal what type of BPSD affects caregiver burden in patients with DLB.Methods: We collected data on neuropsychiatric inventory-plus (NPI-plus), Zarit Burden Interview (ZBI), Mini-Mental State Examination (MMSE), Lawton's Instrumental Activities of Daily Living and Physical Self-Maintenance Scale (IADL/PSMS), age, and sex of 102 patients with probable DLB. An exploratory factor analysis of 13 items of the NPI-plus was carried out to classify BPSD. Multivariate regression analyses were conducted to extract the clinical variables related to caregiver burden, including factors resulting from the aforementioned factor analysis.Results: The mean age and MMSE score were 78.6 (5.6) and 20.2 (5.2), respectively. Factor analysis revealed four factors of “psychosis,” “affection,” “wakefulness,” and “hyperactivity.” “Psychosis” and “affection” factors as well as MMSE, IADL, and PSMS were significantly associated with ZBI. Multivariate regression analyses revealed that the total score of ZBI was associated with “psychosis,” “affection,” and IADL, that the personal strain score of ZBI was associated with “affection” and IADL, and that the role strain score of ZBI was associated with “wakefulness” and IADL.Conclusions: BPSD in DLB consists of three factors common to Alzheimer's disease and a specific “wakefulness” factor. In addition to IADL, each BPSD factor would affect caregiver burden in different ways in DLB.

show abstract

“…Most of the studies discussing dementia and caregiver burden are cross sectional (Huang et al, 2012 ; Yu et al, 2015 ; Hashimoto et al, 2017 ; Torrisi et al, 2017 ; Branger et al, 2018 ; Kawano et al, 2020 ; Lucijanić et al, 2020 ; Jhang et al, 2021 ; Tsai et al, 2021 ). Most of these articles supported that patient neuropsychiatric symptoms (Huang et al, 2012 ; Hashimoto et al, 2017 ; Torrisi et al, 2017 ; Branger et al, 2018 ; Kawano et al, 2020 ; Tsai et al, 2021 ), poor performance of activities for daily living (ADLs) (Hashimoto et al, 2017 ; Kawano et al, 2020 ; Tsai et al, 2021 ), duration of disease (Kawano et al, 2020 ), female gender, and low education level of the caregiver (Jhang et al, 2021 ) increased the caregiving burden. Worse cognitive function (Yu et al, 2015 ), using daily care services, and the male sex of the patient (Lucijanić et al, 2020 ) were also shown to increase the care burden in some cross-sectional articles.…”

Section: Introductionmentioning

confidence: 99%

A Comparison of Caregiver Burden for Different Types of Dementia: An 18-Month Retrospective Cohort Study

et al. 2022

Self Cite

View full text Add to dashboard Cite

BackgroundThis study aimed to elucidate the influence of dementia etiologies on the degree of caregiver burden and determine which factors predict a high caregiving burden.MethodsThis 18-month retrospective cohort study enrolled 630 patients and their caregivers from the Dementia Center of Changhua Christian Hospital. The care team performed face-to-face interviews every 6 months, for 18 months from when a diagnosis of dementia was made. The primary outcome was the change in Zarit Burden Interview (ZBI) scores. Generalized estimating equations were used for the longitudinal data analysis.ResultsParticipants with Lewy body disease (LBD) had a significantly higher caregiving burden compared with those with Alzheimer's disease (AD) (β = 3.83 ± 1.47, Wald = 6.79, p = 0.009) after adjusting for patient and caregiver features. Caregivers of mixed-type dementia and frontotemporal dementia (FTD) experienced a greater burden than caregivers of AD, at 6- and 18-month follow-up. Patients with more severe dementia, neuropsychiatric symptoms, being cared for by more than two caregivers, or utilizing social resources were associated with higher ZBI scores; the depressive mood of caregiver also predicted higher ZBI scores.ConclusionThis longitudinal study demonstrated that caregiver burden was influenced by the underlying dementia etiology of patients. The dementia care team should provide personalized education and transfer patients and caregivers to appropriate resources, especially for high-risk populations.

show abstract

Predictors of caregiver burden in aged caregivers of demented older patients

Cited by 79 publications

References 50 publications

Caregiver strain in progressive supranuclear palsy and corticobasal syndromes

Caregiver strain in progressive supranuclear palsy and corticobasal syndromes

Impact of Behavioral and Psychological Symptoms on Caregiver Burden in Patients With Dementia With Lewy Bodies

A Comparison of Caregiver Burden for Different Types of Dementia: An 18-Month Retrospective Cohort Study

Contact Info

Product

Resources

About