Predictors of Carotid Atherosclerosis Progression: Evidence from an Ultrasonography Laboratory

Abstract

Background and purpose: The purpose of this study was to investigate the role of risk factors in predicting the variation in carotid atherosclerosis at ultrasonographic follow-up and, therefore, its role in the progression of large-vessel disease. Methods: This retrospective population study included all the outpatients that underwent at least two carotid ultrasonographies at our laboratory from 2001 to 2017. Demographic data, vascular risk factors, and the results at follow-up were analysed to determine if correlations exist between these risk factors and variation in carotid atherosclerosis. Results: Data from 600 patients (327 males and 273 females with a mean age of 67 years) were collected. The mean follow-up period was 49 months (range: 1–195). We analysed each demographic variable and risk factor to assess its correlation with a worsening of carotid atherosclerosis; previous myocardial infarction (2.594), previous carotid surgical treatment (2.368), and hypertension (1.85) were found to have the highest odds ratios, respectively. Furthermore, the sample was divided into specific subpopulations (diabetes, hypertension, and smoking), and an association was found between age and worsening stenosis. Discussion and conclusions: Our results confirm the importance of carotid ultrasonographic follow-up in the monitoring and managing of large-vessel disease. Myocardial infarction, previous stroke, and previous surgical treatment were the strongest predictors of a worsening of carotid atherosclerosis. These findings suggest a strict follow-up is needed, even in the absence of significant carotid atherosclerosis at baseline.

Editorial: Neurosonology in stroke medicine and neurocritical care

“…Early identification of high-risk features through Neurosonology expedites intervention in strokes of various etiologies ( 5 ). Furthermore, Neurolosonolgy follow-up enhances the precision of therapeutic strategies, adding predictive information ( 6 ).…”

Association of fatty pancreas and subclinical atherosclerosis: A cross-sectional analysis

“…Kadir et al 9 reported that NAFLD can be used as an independent risk factor for predicting subclinical atherosclerosis, which is closely related to cardiovascular events, and carotid plaque is a strong predictor of cardiovascular events 10 . Carotid ultrasound follow-up plays an important role in the monitoring and management of adverse cardiovascular events and can be used to noninvasively monitor the presence of subclinical atherosclerosis 11 . Studies have shown that FP is independently correlated with carotid intima-media thickness (CIMT) 12 .…”