Predictors of Gastrointestinal Transit Times in Colon Capsule Endoscopy

Moen, Sarah; Vuik, Fanny E.; Voortman, Trudy; Kuipers, Ernst J.; Spaander, Manon C.W.

doi:10.14309/ctg.0000000000000498

Cited by 2 publications

(3 citation statements)

References 34 publications

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“…A comparable study to ours conducted by Moen et al has recently been published 21 . In their similarly sized study (n=451), they found a range of predictors associated with a complete test, including increased patient age, which contradicts our results.…”

Section: Discussionsupporting

confidence: 87%

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Associations between patient factors and successful colon capsule endoscopy – A prospective cohort study

MacLeod,

Foxton,

Wilson

et al. 2023

Colorectal Disease

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AimTo establish patient factors associated with a successful colon capsule endoscopy (CCE) test.MethodThis prospective cohort study used data collected from patients who underwent CCE as part of the ScotCap evaluation prior to April 2020. A CCE was defined as successful if the capsule visualized the whole colon and rectum (complete test) with sufficient bowel cleansing to permit assessment of the colonic mucosa (adequate bowel preparation). Factors from patients in symptomatic and surveillance groups were analysed for associations with a successful test, complete test, adequate bowel preparation and requirement for further procedure using univariate, multivariate logistic, least absolute shrinkage and selection operator regression.ResultsData from 263 symptomatic and 137 surveillance patients were analysed. There was an association between a symptomatic patient's age and a successful test (OR = 0.97, 95% CI: 0.95–0.99), adequate bowel preparation (OR = 0.97, 95% CI: 0.94–1.00) and further procedure requirement (OR = 1.04, 95% CI: 1.02–1.06). An association was found, for symptomatic patients, between a faecal immunochemical test result in the range 10–399 μg/g and a further procedure (OR = 2.32, 95% CI: 1.23–4.48). In patients undergoing surveillance for previous colorectal cancer (OR = 0.42, 95% CI: 0.18–0.97), had previous bowel resection surgery (OR = 0.43, 95% CI: 0.19–0.98) or took a beta blocker medication (OR = 0.32, 95% CI: 0.11–0.88), an association was found with further procedure requirement.ConclusionsAmong symptomatic patients, younger age was associated with obtaining a successful CCE test. Clinicians could consider patient selection based on these results to improve the rate of successful testing in clinical practice.

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Section: Discussionsupporting

confidence: 87%

“…A comparable study to ours, conducted by Moen et al., has recently been published [21]. In their similarly sized study ( n = 451), Moen et al.…”

Section: Discussionsupporting

confidence: 79%

Associations between patient factors and successful colon capsule endoscopy – A prospective cohort study

MacLeod,

Foxton,

Wilson

et al. 2023

Colorectal Disease

View full text Add to dashboard Cite

show abstract

“…A recent study conducted in Nederland by Moen et al . 39 examined the factors affecting transit times in CCE. The study, which included 451 participants, is the largest to date to investigate possible predictors of CCE transit times.…”

Section: Influential Factors Affecting Cr In Ccementioning

confidence: 99%

Clinical utility of colon capsule endoscopy: a moving target?

Jalayeri Nia,

Arasaradnam,

Koulaouzidis

2023

Therap Adv Gastroenterol

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The purpose of this article is to provide an overview of white light colon capsule endoscopy’s current clinical application, concentrating on its most recent developments. Second-generation colon capsule endoscopy (CCE2) is approved by the FDA for use as an adjunctive test in patients with incomplete colonoscopy and within Europe in patients at average risk, those with incomplete colonoscopies or those unwilling to undergo conventional colonoscopies. Since the publication of European Society of GI Endoscopy guidelines on the use of CCE, there has been a significant increase in comparative studies on the diagnostic yield of CCE. This paper discusses CCE2 in further detail. It explains newly developed colon capsule system and the current status on the use of CCE, it also provides a comprehensive summary of systematic reviews on the implementation of CCE in colorectal cancer screening from a methodological perspective. Patients with ulcerative colitis can benefit from CCE2 in terms of assessing mucosal inflammation. As part of this review, performance of CCE2 for assessing disease severity in ulcerative colitis is compared with colonoscopy. Finally, an assessment if CCE can become a cost-effective clinical service overall.

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Predictors of Gastrointestinal Transit Times in Colon Capsule Endoscopy

Cited by 2 publications

References 34 publications

Associations between patient factors and successful colon capsule endoscopy – A prospective cohort study

Associations between patient factors and successful colon capsule endoscopy – A prospective cohort study

Clinical utility of colon capsule endoscopy: a moving target?

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