Predictors of home oxygen duration in chronic neonatal lung disease

Wong, Matthew; Neylan, Melissa; Williams, Gordon H.; Zahir, Syeda Farah; Chawla, Jasneek

doi:10.22541/au.160071418.89113760

Cited by 1 publication

(3 citation statements)

References 21 publications

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“…Most published reports describe discontinuation of HOT at over 12 months CGA, with some infants' durations of HOT exceeding 18 months. 2,3,5,10 Extended duration of HOT causes additional stress to families, increased health-care utilization, and increased health-care costs. 6,7,15,16 Creating guidelines that optimize HOT utilization and decrease duration is a priority for families, researchers, and clinicians.…”

Section: Discussionmentioning

confidence: 99%

“…Factors contributing to longer durations of HOT have been described previously, and include longer NICU LOS, hypercarbia at term CGA, and higher initial flow rates. 10,17 Prior studies have all been retrospective in design. Consistent with these studies, our prospective study confirmed the association of higher O 2 flow rate at NICU discharge with a longer duration of HOT.…”

Section: Discussionmentioning

confidence: 99%

“…6 Recent studies have described that implementation of standardized management guidelines results in shorter durations of HOT, and utilization of recorded oximetry can further decrease the time spent on HOT. [8][9][10] Lack of information about O 2 duration and the weaning trajectory cause unnecessary parental stress and anxiety. Identification of potential risk factors leading to increased durations of HOT in infants with BPD using the newly adapted weaning strategies may improve clinicians' ability to optimally counsel families, set realistic expectations, and selectively target resources to the highest risk patients.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Duration of Home Oxygen Therapy in Preterm Infants Utilizing a Remote Patient Monitoring Program to Wean: Trajectory Patterns

White

Lee

Rhein

2023

Journal of Neonatology

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Background Up to one-third of preterm infants diagnosed with bronchopulmonary dysplasia will require home oxygen therapy (HOT) after hospital discharge. Currently, no consensus-based guidelines exist for safely managing HOT. The Recorded Home Oximetry (RHO) trial was the first to evaluate a structured weaning guideline. At the conclusion of the trial, our home institution implemented the RHO program in June 2019, utilizing the same RHO protocol as the original trial. The purpose of this project was to evaluate the duration and weaning trajectory of infants followed and identify any risk factors associated with flow rate increases or longer trajectories. Methods This is a prospective analysis of infants born <37 weeks gestation followed by the RHO program between June 2019 and June 2021. Results The study included 26 infants with a total of 407 RHO epochs. There was nearly equal distribution of males and females with a mean birth gestational age of 27.5 (±3.4 SD) weeks. The median time of successful discontinuation of HOT was 2.1 months. Infants starting on higher initial flow rates had faster weaning trajectories compared to those who started on lower flow rates ( P value <.0001). Infants born small for gestational age were about twice as likely to have longer maintenance on one flow rate compared to appropriate for gestational age infants (RR = 2.81, 95% CL 1.64-4.81, P = .0002). Conclusion The RHO program, a structured telemedicine weaning guideline, reduces the duration of HOT in preterm infants and does not cause unnecessary swings in oxygen flow rates.

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