Predictors of Inflammatory Local Recurrence after Breast - Conserving Therapy for Breast Cancer : Matched Case-Control Study

Abstract

Ipsilateral breast tumor recurrence (IBTR) after breastconserving surgery (BCS) and whole-breast radiation occurs in 4% to 10% of patients [1][2][3]. Late local recurrence (> 2 years) in a conserved breast can usually be treated by further surgery with curative intent and remains associated with a favorable prognosis [4][5]. Early local recurrence (< 2 years) may indicate a more aggres-sive clinicobiological behavior that heralds the appearance of distant metastases in many cases [1,[6][7]. A small but important subset of patients with local recurrence develops inflammatory local recurrence (ILR), which is associated with a distinctly poorer prognosis. An uncommon finding representing 7% to 20% of recurrences [8][9][10][11][12], sometimes referred to as "secondary" inflammatory breast cancer, ILR typically occurs within two years of BCS, exhibits clinical and pathological characteristics of of inflammatory local recurrence after breast-conserving therapy for breast cancer: Matched case-control study. J Med Liban 2015 ; 63 (4) : 171-178.Akoum R, Abdalla EK, Saade M, Awdeh A, Abi-Aad F, Bejjani N, Ghossain A, Brihi E, Audi A. Facteurs prédictifs de récidive locale inflammatoire après chirurgie conservatrice du cancer du sein : Étude comparative cas-témoins.