Predictors of inotrope use during separation from cardiopulmonary bypass

“…60 The postbypass phase, on the other hand, is a labile period during which there are frequent changes in preload and afterload, inotropic and chronotropic drugs may be in effect, and the heart is frequently electrically paced. 61 All of the above factors must be considered during the echocardiographic assessment of prosthetic valve function.…”

Section: Considerations For Intraoperative Patientsmentioning

confidence: 99%

Recommendations for Evaluation of Prosthetic Valves With Echocardiography and Doppler Ultrasound

Zoghbi¹,

Chambers²,

Dumesnil³

et al. 2009

Journal of the American Society of Echocardiography

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1,160

357

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“…Thus, restrictive use of inotropes would be particularly desirable in patients with limited cardiac reserve. On the other hand, patients with preoperatively compromised left ventricular function are particularly prone to require treatment for postoperative cardiac failure (6,7). Accordingly, postoperative morbidity and mortality is more frequently encountered in patients with preoperatively compromised left ventricular function .…”

Section: Introductionmentioning

confidence: 99%

A metabolic protective strategy could improve long-term survival in patients with LV-dysfunction undergoing CABG

Svedjeholm

Vidlund²,

Vanhanen

et al. 2010

Scandinavian Cardiovascular Journal

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Hemodynamic state was primarily assessed by mixed venous oxygen saturation (SvO 2 ).Follow-up averaged 9.7±1.4 years.Results LVEF was 0.30 ± 0.05 (range 0.20-0.37) and 3.5 ± 1.3 vessels were bypassed.Inotropes were used in 6.7% for weaning from CPB. Increase of s-creatinine by 50% compared to preoperative values was observed in 2.9 %. Logistic EuroSCORE was 8.3%whereas observed 30-day mortality was 1.0%. Crude 5-year survival was 89.4%. ConclusionsThe metabolic strategy allowed restrictive use of inotropes and was associated with encouraging long-term survival. Renal function was well preserved suggesting that SvO 2 served as an adequate marker of circulation. Randomized trials with metabolic support are warranted.

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Predictors of inotrope use during separation from cardiopulmonary bypass

Cited by 55 publications

References 23 publications

Mitral Regurgitation and Coronary Artery Bypass Surgery: Comparison of Mitral Valve Repair and Replacement

Mitral Regurgitation and Coronary Artery Bypass Surgery: Comparison of Mitral Valve Repair and Replacement

Recommendations for Evaluation of Prosthetic Valves With Echocardiography and Doppler Ultrasound

A metabolic protective strategy could improve long-term survival in patients with LV-dysfunction undergoing CABG

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