Predictors of late recurrence of atrial fibrillation after catheter ablation

Does a blanking period after pulmonary vein isolation impact long-term results? Results after 55 months of follow-up

“…The available publications during the patient enrolment phase showed no association between early AF recurrence and long-term results [7]. This is opposite to the data presented by Arya et al [16] and Cai et al [6]. In the first study, the independent risk factors for late AF recurrence were: early AF recurrence (HR 4.3; 95% CI 2.0-9.1; p = 0.0001), left atrial diameter ≥ 50 mm (HR 4.6; 95% CI 2.9-9.1; p = 0.0001), and hypertension (HR 3.3; 95% CI 1.4-7.5; p = 0.003); in the second, the risk factors were overweight (HR 4.71; 95% CI 1.71-12.98; p = 0.003), metabolic syndrome (HR 4.41; 95% CI 1.56-12.46; p = 0.005), and early AF recurrence (HR 3.18; 95% CI 1.07-9.44; p = 0.037).…”

“…Furthermore, it is not clearly defined when the early periods ends and when the late period starts. Previously, AF recurrences during the first weeks after PVI were treated as a non-significant factor, but nowadays they are regarded to have an impact on long-term PVI failure [5][6][7].…”

Predictors of atrial fibrillation recurrence after atrial fibrillation ablation with cryoballoon

“…In previous RF ablation studies early recurrence was observed in 33.8-54% of patients [32][33][34][35], so early recurrence was traditionally seen as a benign process not affecting long term results. Then, a lot of studies showed that ERAF was an important risk factor for late recurrence of AF [33,[35][36][37][38][39][40].…”

“…Then, a lot of studies showed that ERAF was an important risk factor for late recurrence of AF [33,[35][36][37][38][39][40]. The possible causes of ERAF are: (1) transient stimulatory effect of acute inflammatory response following the histopathologic tissue damage that resulted from RF energy; (2) reconnection of electrical conduction between the LA and PVs and/or resumption of electrical activity in pre-ablation lines; (3) non-PV foci triggering AF, and (4) transient imbalance of autonomic nervous system [35].…”

Catheter radiofrequency ablation in atrial fibrillation and flutter management in patients with comorbidities

“…L. Cai и соавт. [41] в качестве предикторов развития ФП после проведения РЧА устья легочных вен рассматривают ожи-рение и метаболический синдром. Еще одним предикто-ром рецидива аритмии после РЧА является женский пол [42].…”