Purpose
Mentored K (K01/K08/K23) career development awards are positively associated with physicians’ success as independent investigators; however, individuals in some racial/ethnic groups are less likely than others to receive this federal funding. The authors sought to identify variables that can explain (mediate) the association between race/ethnicity and mentored K award receipt among U.S. LCME-accredited medical school graduates who planned research-related careers.
Method
The authors analyzed de-identified data from the Association of American Medical Colleges and from the National Institutes of Health Information for Management, Planning, Analysis, and Coordination II grants database for a national cohort of 28,690 graduates from 1997–2004 who planned research-related careers, followed through August 2014. The authors examined ten potential mediators (four research activities, two academic-performance measures, medical-school research intensity, degree program, debt, and specialty) of the association between race/ethnicity and mentored K award receipt in models comparing underrepresented minorities in medicine (URM) and non-URM graduates.
Results
Among 27,521 graduates with complete data (95.9% of study-eligible graduates), 1,147 (4.2 %) received mentored K awards, including 79 of 3,341 URM (2.4%) and 1,068 of 24,180 non-URM (4.4%) graduates. Nine variables (all but debt) were significant mediators and together they explained 96.2% (95% confidence interval, 79.1%–100%) of the association between race/ethnicity and mentored K award receipt.
Conclusions
Research-related activities during and after medical school and standardized academic measures largely explained the association between race/ethnicity and mentored K award receipt in this national cohort. Interventions targeting these mediators could mitigate racial/ethnic disparities in the federally funded physician-scientist research workforce.