“…Type 2 NF involves group A Streptococcus (GAS) infection, with or without a concomitant streptococcal infection, and it can occur in any age group even in the absence of any complicated medical illness. Indeed, only a single micro-organism is found in the blood of 27% of NF patients, whereas multiple micro-organisms are identified in the blood of 2% of NF patients and no micro-organisms are found in 71% of NF cases (15). Streptococcus spp., S. aureus, V. vulnificus, A. hydrophila, Enterobacteriaceae (Escherichia coli, Pseudomonas spp., and Klebsiella spp.)…”