Predictors of neurodevelopmental outcome for preterm infants with brain injury: MRI, medical and environmental factors

Badr, Lina Kurdahi; Bookheimer, Susan Y.; Purdy, Isabell B.; Deeb, Mary

doi:10.1016/j.earlhumdev.2008.11.005

Cited by 52 publications

(30 citation statements)

References 47 publications

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“…During the early years of the child's life, motor and cognitive development seems to be synchronous, particularly from the six months of age 9 . Statistically significant correlation between the results of the AIMS and Bayley-II scales in children at 6 and 12 months 28 and in preterm infants of 12 and 18 months 29 have been reported, confirming our results. Recent study found a positive correlation of motor skills with cognitive skills 30 , a result similar to the present study.…”

Section: Discussionsupporting

confidence: 91%

Desenvolvimento motor e cognitivo de bebês de mães adolescentes e adultas: estudo longitudinal

Borba

Valentini

2015

Rev. Bras. Cineantropom. Desempenho Hum.

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-The aims of this study were to investigate in infants of adolescent and adult mothers: (1) the risk factors for child development; (2) changes in cognitive and motor development over four months of follow-up, (3) correlation between cognitive and motor development over four months of follow-up. This is a longitudinal study with 40 infants, 20 infants of adolescent mothers and 20 of adult mothers from Porto Alegre and Butiá, state of Rio Grande do Sul, Brazil. Three evaluations of motor and cognitive development were performed using the Alberta Motor Infant Scale (AIMS) and the Bayley Scale Infant Development II. Significant difference in the supine position of AIMS was observed between groups in the third evaluation. Infants of adolescent mothers showed lower scores than those of adult mothers. The motor scores of each position and total AIMS score showed significant difference during overall time and in each group. The Bayley-II mental score also showed significant difference during overall time and in each group. There was a positive, strong and significant association between AIMS and Bayley scores in all three evaluation stages as in the group of infants of adolescent and adult mothers. It was concluded that infants of adolescent mothers showed worse results in the supine position during the third evaluation than those of adult mothers. There was a significant association between motor and cognitive development in both groups of infants over time. Key words: Infant development; Longitudinal study; Pregnancy in adolescence. Resumo -Este estudo teve como objetivos investigar em bebês de mães adolescentes e adultas: (1) os fatores de risco para o desenvolvimento infantil; (2) as mudanças cognitivas e motoras ao longo de quatro meses, (3) as correlações entre o desenvolvimento motor e cognitivo ao longo de quatro meses. Estudo longitudinal com 40 bebês, 20 nascidos de mães adolescentes e 20 de mães adultas, provenientes dos municípios de

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Section: Discussionsupporting

confidence: 91%

Desenvolvimento motor e cognitivo de bebês de mães adolescentes e adultas: estudo longitudinal

Borba

Valentini

2015

Rev. Bras. Cineantropom. Desempenho Hum.

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“…In earlier studies, associations between brain volumes at term equivalent age and later outcome have been analysed up to 2 years of age, and in those studies altered volumes have been shown to relate to impaired development [4,6,13,22,28,29,34,42]. Connections between brain volumes and development have also been found later in childhood and adolescence [1,3,21,24], but volumes have then been measured simultaneously with a developmental assessment and, hence, the predictive value of smaller or larger volumes has not been considered.…”

Section: Discussionmentioning

confidence: 99%

“…The significance of altered brain volumes on preterm children's development has been at the centre of interest in several studies. Altered volumes at term equivalent age have been shown to associate with an impaired development at 1 year [4,13], at 18 months [4], at 18-20 months [22], and at 2 years of corrected age [6,28,29,34,42]. So far, there have been no previous studies on the relationship between the brain volumes at term equivalent age and the outcome beyond 2 years corrected age.…”

Section: Introductionmentioning

confidence: 99%

Relations between brain volumes, neuropsychological assessment and parental questionnaire in prematurely born children

Lind

Haataja

Rautava

et al. 2009

Eur Child Adolesc Psychiatry

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The objective of this study is to assess the relationship between brain volumes at term equivalent age and neuropsychological functions at 5 years of age in very low birth weight (VLBW) children, and to compare the results from a neuropsychological assessment and a parental questionnaire at 5 years of age. The study group included a regional cohort of 97 VLBW children and a control group of 161 children born at term. At term equivalent age, brain magnetic resonance imaging (MRI) was performed on the VLBW children, and analysed for total and regional brain volumes. At 5 years of age, a psychologist assessed the neuropsychological performance with NEPSY II, and parents completed the Five to fifteen (FTF) questionnaire on development and behaviour. The results of the control group were used to give the age-specific reference values. No significant associations were found between the brain volumes and the NEPSY II domains. As for the FTF, significant associations were found between a smaller total brain tissue volume and poorer executive functions, between a smaller cerebellar volume and both poorer executive functions and motor skills, and, surprisingly, between a larger volume of brainstem and poorer language functions. Even after adjustment for total brain tissue volume, the two associations between the cerebellar volume and the FTF domains remained borderline significant (P = 0.05). The NEPSY II domains Executive Functioning, Language and Motor Skills were significantly associated with the corresponding FTF domains. In conclusion, altered brain volumes at term equivalent age appear to affect development still at 5 years of age. The FTF seems to be a good instrument when used in combination with other neuropsychological assessment

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“…Greater efficiency in predicting the risk of development may improve the selection of eligible infants for early therapeutic strategies 9 . Several predictive studies have been performed using neonatal and maternal risk factors to predict the outcome of development in preterm newborn infants at different ages [10][11][12][13][14] . However, these studies did not mention the use of neurobehavioural responses of premature newborn infants in the neonatal period (prior to term age) to predict global and motor outcomes prior to the end of the first year.…”

mentioning

confidence: 99%

Predictive models of early motor development in preterm infants: a longitudinal-prospective study

Formiga

Vieira

Facundes

et al. 2017

J. Hum. Growth Dev.

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Introduction: Preterm infants are vulnerable to developmental delays. Detecting problems at an early age is one of the challenges of professionals and researchers in the area. Objective: To analyse the motor development and to identify the risk factors associated with predictors of overall and motor delay in preterm newborns. Methods: Eighty preterm infants (50% female; mean gestational age = 33 ± 2.2 weeks) with low birth weight (average of 1,715 ± 437 g) were evaluated using the Neurobehavioral Assessment of the Preterm Infant (NAPI) during the neonatal phase (prior to term age), the Denver Developmental Screening Test II (DDST-II) between 2 and 8 months, the Test of Infant Motor Performance between 2 and 4 months regarding motor development and the Alberta Infant Motor Scale between 4 and 8 months. Results: Neurobehavioural delay was noted in 24% of the infants in the neonatal phase. Between 2 and 8 months, the delay in overall development was ≥ 31% and the delay in motor development was 35-36 %. Decreased levels of alertness, orientation, motor development and vigour according to the NAPI were shown to be predictive of a delay in development between 4 and 6 months of age. The delay in overall development between 2 and 6 months was predictive of a delay in motor development between 6 and 8 months. Conclusion: Neurobehavioural variables, hospital stay and overall delay are good predictors of motor development during the first year of age. Suggested citation: Formiga CKMR, Vieira MEB, Fagundes RR, Linhares MBM. Predictive models of early motor development in preterm infants: a longitudinal-prospective study. Keywords

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Predictors of neurodevelopmental outcome for preterm infants with brain injury: MRI, medical and environmental factors

Cited by 52 publications

References 47 publications

Desenvolvimento motor e cognitivo de bebês de mães adolescentes e adultas: estudo longitudinal

Desenvolvimento motor e cognitivo de bebês de mães adolescentes e adultas: estudo longitudinal

Relations between brain volumes, neuropsychological assessment and parental questionnaire in prematurely born children

Predictive models of early motor development in preterm infants: a longitudinal-prospective study

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