Predictors of Operative Mortality in Critical Valvular Aortic Stenosis Presenting in Infancy

Hammon, John W.; Lupinetti, Flavian M.; Maples, Michael D.; Merrill, Walter H.; Frist, William H.; Graham, T.P.; Bender, Harvey W.

doi:10.1016/s0003-4975(10)64527-4

Cited by 86 publications

(30 citation statements)

References 25 publications

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“…1,2 LV volumes have and continue to be used as key determinants of suitability for 1-versus 2-ventricular repair. 3,4 To date, measurements have been based on 2D echocardiography, applying formulas that make inherent assumptions about LV geometry. However, in young pediatric patients with complex CHD, the LV is distorted and does not assume a typical ellipsoid shape, limiting the accuracy of 2D echocardiographic evaluation of mass and volumes.…”

mentioning

confidence: 99%

Validation of 3D Echocardiographic Assessment of Left Ventricular Volumes, Mass, and Ejection Fraction in Neonates and Infants With Congenital Heart Disease

Friedberg

Tworetzky

et al. 2010

Circ: Cardiovascular Imaging

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Background-Quantitative assessment and validation of left ventricular (LV) volumes and mass in neonates and infantswith complex congenital heart disease (CHD) is important for clinical management but has not been undertaken. We compared matrix-array 3D echocardiography (3D echo) measurements of volumes, mass, and ejection fraction (EF) with those measured by cardiac MRI in young patients with CHD and small LVs because of either young age or LV hypoplasia. Methods and Results-Thirty-five patients aged Ͻ4 years (median, 0.8 years) undergoing MRI were prospectively enrolled. Three-dimensional echo was acquired immediately after MRI, and volume, mass, and EF measurements, using summation of discs methodology, were compared with MRI.

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confidence: 99%

Validation of 3D Echocardiographic Assessment of Left Ventricular Volumes, Mass, and Ejection Fraction in Neonates and Infants With Congenital Heart Disease

Friedberg

Tworetzky

et al. 2010

Circ: Cardiovascular Imaging

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“…Like other investigators, 5,9,10 we found several patients who survived a biventricular approach with LVEDV/BSA of 15 to 20 mL/m 2 , well below the reported threshold value for patients with critical aortic valve stenosis. 15 In addition to individual independent risk factors predictive of a failed biventricular approach, several combinations of lesions appeared to be predictive of poor outcome. For example, 80% of patients with a moderate/large VSD and LVEDV z-score ϽϪ2 were in the failed 2V group.…”

Section: Discussionmentioning

confidence: 96%

Predictors of Outcome of Biventricular Repair in Infants With Multiple Left Heart Obstructive Lesions

2001

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Background-Decisions regarding surgical strategy in patients with multiple left heart obstructive or hypoplastic lesions often must be made in the newborn period and are seldom reversible. Predictors of outcome of biventricular repair have not been well defined in this heterogeneous group of patients, and risk factors described for critical aortic valve stenosis have been shown to be inapplicable to patients with other left heart obstructive lesions. The goal of this study was to identify echocardiographic predictors of outcome of biventricular repair for infants with multiple left heart obstructive lesions. Methods and Results-Patients with Ն2 areas of left heart obstruction or hypoplasia, diagnosed at Յ3 months of age, who had not previously undergone surgical or catheter intervention and maintained biventricular physiology were included (nϭ72). Failure of biventricular repair was defined as takedown to a univentricular repair, cardiac transplantation, and/or death (nϭ14; 19%). This group was compared with the patients who survived a biventricular approach (nϭ58

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“…This distinction is essential in deciding whether to proceed with a Norwood-type single ventricle repair or cardiac transplantation instead of valvotomy or valve replacement procedures. Previous reports have described significantly worse results in those patients requiring a "crossover" between univentricular and biventricular strategies [17,18].…”

Section: Valvar Aortic Stenosismentioning

confidence: 89%

Left Ventricular Outflow Tract Obstruction

Tchervenkov

Bernier

Del

et al. 2012

Pediatric Cardiac Surgery

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Predictors of Operative Mortality in Critical Valvular Aortic Stenosis Presenting in Infancy

Cited by 86 publications

References 25 publications

Validation of 3D Echocardiographic Assessment of Left Ventricular Volumes, Mass, and Ejection Fraction in Neonates and Infants With Congenital Heart Disease

Validation of 3D Echocardiographic Assessment of Left Ventricular Volumes, Mass, and Ejection Fraction in Neonates and Infants With Congenital Heart Disease

Predictors of Outcome of Biventricular Repair in Infants With Multiple Left Heart Obstructive Lesions

Left Ventricular Outflow Tract Obstruction

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