Predictors of outcome in cryptoglandular anal fistula according to magnetic resonance imaging: A systematic review

Teymouri, Alireza; Keshvari, Amir; Ashjaei, Ali; Ahmadi Tafti, Seyed Mohsen; Salahshour, Faeze; Khorasanizadeh, Faezeh; Naseri, Amirhosein

doi:10.1002/hsr2.1354

Cited by 3 publications

(1 citation statement)

References 38 publications

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“…It's very useful to value extrasphincteric plans, but more difficultly differentiates sphincteric muscles. (6) Fistulography has been displaced by ultrasound and MRI. Most likely, its use must be restricted nowadays in cases in which these two explorations don't contribute useful data.…”

Section: Diagnosticmentioning

confidence: 99%

Experiencia en el tratamiento de las fístulas perianales complejas en un hospital público. 2018-2022

Santacruz-Bareiro

2024

Cir. parag.

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Introducción: El tratamiento de la fistula perianal compleja es controvertido, requiere de un conocimiento anatómico preciso y de métodos auxiliares de diagnóstico para ofrecer el mejor resultado posible al paciente. Objetivos: Describir la experiencia en el tratamiento de las Fístulas Perianales complejas en un Hospital Público en el periodo 2018 - 2022. Material y Métodos: Estudio observacional descriptivo de corte transversal, no probabilístico de casos consecutivos de pacientes con diagnóstico de fistula perianal compleja ingresados en el servicio de coloproctología del Hospital Nacional de Itauguá en el periodo de enero de 2018 hasta diciembre de 2022, de los cuales 21 cumplen con los criterios de inclusión de fistula perianal compleja. Resultados: De los 21 pacientes, 76% fueron hombres, con una media de edad de 35 años ± 10, el principal motivo de consulta fue secreción anal en 19 pacientes. En cuanto al tipo de fístula se identificó un 81% de fístula transesfinteriana alta, en cuanto al tratamiento, se realizó en un 48% fistulectomìas, en cuanto a las complicaciones, solo en un 10 % de los pacientes se constató recidiva de la fístula que fue tratada con fistulotomía con colocación sedal. Conclusión: La fístula perianal compleja es una patología periorificial poco frecuente, son fundamentales los datos obtenidos por el examen físico y la posibilidad de efectuar estudios complementarios con recursos tecnológicos avanzados para su resolución satisfactoria.

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Section: Diagnosticmentioning

confidence: 99%

Experiencia en el tratamiento de las fístulas perianales complejas en un hospital público. 2018-2022

Santacruz-Bareiro

2024

Cir. parag.

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Improving High Anal Fistula Management: Insights from Transanal Opening of Intersphincteric Space (TROPIS) - A Retrospective Cohort Study

Zhan

2024

Preprint

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Objective This retrospective cohort study assessed the therapeutic efficacy and safety profile of the transanal opening of the intersphincteric space (TROPIS) procedure for the treatment of complex high anal fistulas. Methods A retrospective cohort study was conducted, including 131 patients who underwent TROPIS surgery at the First Hospital of Harbin from May 2023 to April 2024. A control group of 124 patients with high anal fistulas was treated with open drainage and seton placement by the same attending physician at the same hospital from January 2022 to April 2023. The study compared clinical outcomes, postoperative pain, wound healing, anal sphincter function, anorectal manometry, quality of life, postoperative complications, and recurrence rates between the two groups. Results The TROPIS group demonstrated a total effectiveness rate of 100.0%, significantly surpassing the control group's rate of 84.8% (P < 0.05). Postoperative pain, wound healing duration, and anal sphincter scores were markedly lower in the TROPIS group compared to the control group (P < 0.05). Both groups experienced a significant reduction in Wexner incontinence scores postoperatively, with the TROPIS group showing a more pronounced improvement (P < 0.05). Anorectal pressures, encompassing both resting and maximum pressures, were significantly elevated in the TROPIS group relative to the control group within one month postoperatively (P < 0.05). Quality of life, as assessed by the SF-36 questionnaire, indicated a more substantial improvement in the TROPIS group than in the control group (P < 0.05). Furthermore, the rate of postoperative complications was notably lower in the TROPIS group than in the control group (P < 0.05). Conclusion TROPIS has demonstrated superior clinical outcomes in the management of high anal fistulas, characterized by diminished postoperative pain, enhanced anal sphincter functionality, improved quality of life, and a reduction in postoperative complications. These results endorse the continued promotion and application of TROPIS as a viable treatment modality for high anal fistulas.

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The association between VEGF genetic variations and the risk of bronchopulmonary dysplasia in premature infants: a meta-analysis and systematic review

Golshan-Tafti,

Bahrami,

Dastgheib

et al. 2024

Front. Pediatr.

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ObjectivePrevious studies on the link between VEGF gene polymorphisms and bronchopulmonary dysplasia (BPD) have yielded inconsistent results. This meta-analysis sought to clarify the relationship between genetic variations in the VEGF gene and the risk of BPD.MethodsData were collected from multiple databases, including PubMed, Scopus, EMBASE, and CNKI, up to January 5, 2024.ResultsNineteen case-control studies were analyzed, featuring 1,051 BPD cases and 1,726 healthy neonates. The analysis included four studies on the −460T/C polymorphism (312 cases, 536 controls), four on the −2578C/A polymorphism (155 cases, 279 controls), six on the +405G/C polymorphism (329 cases, 385 controls), and five on the +936C/T polymorphism (225 cases, 526 controls). The meta-analysis suggests that the −460T/C polymorphism may protect against BPD (C vs. T: OR = 0.715, 95% CI 0.543–0.941, p = 0.017; CC vs. TT: OR = 0.478, 95% CI 0.233–0.983, p = 0.045; CC vs. CT + TT: OR = 0.435, 95% CI 0.248–0.764, p = 0.004). No significant associations were found between the −2578C/A, +405G/C, and +936C/T polymorphisms and BPD susceptibility.ConclusionsThis meta-analysis indicates that the C allele of the −460T/C polymorphism may offer protection against BPD. No significant associations were observed for the −2578C/A, +405G/C, and +936C/T polymorphisms.

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Predictors of outcome in cryptoglandular anal fistula according to magnetic resonance imaging: A systematic review

Cited by 3 publications

References 38 publications

Experiencia en el tratamiento de las fístulas perianales complejas en un hospital público. 2018-2022

Experiencia en el tratamiento de las fístulas perianales complejas en un hospital público. 2018-2022

Improving High Anal Fistula Management: Insights from Transanal Opening of Intersphincteric Space (TROPIS) - A Retrospective Cohort Study

The association between VEGF genetic variations and the risk of bronchopulmonary dysplasia in premature infants: a meta-analysis and systematic review

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