Objective: Chronic subdural hematoma (CSDH) is a frequently encountered entity in neurosurgery. The objective of this study was to describe the use of unbiased Cavalieri principle to assess CSDH volume to total brain volume fraction (Percentage) and compare it with the clinical features of the patients. Methods: A total of 33 patients were included in the study. Computed tomography (CT) was acquired from the hospital-imaging database. The ratio of hematoma volume, brain volume, and hematoma volume to brain volume were measured via CT by two clinicians. Measurements were compared with clinical findings. Results: The sample consisted of 22 males and 11 females and mean age 67,27±12,63 years. The measured hematoma volume was 89,78 ± 54,13 cm3, the brain volume was 1329,91 ± 2098,35 cm3 and the percentage volume was 8,14 ± 4,92 cm3. The brain volume values of the cases with impaired consciousness were found to be statistically significant (p <0.05). Conclusions: It should be kept in mind that the bleeding volume of patients with vomiting may be higher.