Purpose This study aimed to identify factors that have been studied for their associations with National Licensing Examination (ENA M) score s in Peru.Methods A search was conducted of literature databases and regist e rs , including EMBASE, SciELO , Web of Science, MEDLINE, Peru s National Register of Research Work and Google Scholar . T he following key terms were used: “ENAM” and a ssociated f actors S tudies in English and Spanish were included. The quality of the included studies was evaluated using the Medical Education Research Study Quality Instrument MERSQIResults In total, 38,500 participants were enrolled in 12 studies. Most (11/12) studies were cross sectional, except for one case control study . Three studies were published in peer reviewed journals. The mean MERSQI was 10.33. A better performance on the ENAM was associated with a higher grade point average ( GPA (n=8), internship setting in EsSalud (n=4) and regular academic status (n=3). Other factors showed associations in various studies , such as med ical school, internship setting, age, gender , socioeconomic status, simulations test, study resources, preparation time, learning styles, study techniques, test anxiety, and self regulated learning strategies.Conclusion The ENAM is a multifactorial phenomenon; our model gives students a locus of control on what they can do to improve their score ( i .e., implement self regulated learning strategies) and faculty, health policymakers, and managers a framework to improve the ENAM score ( i .e ., de sign remediation programs to improve GPA and integrate anxiety management courses in to the curriculum)