Predictors of post-stroke cognitive impairment at three-month following first episode of stroke among patients attended at tertiary hospitals in Dodoma, central Tanzania: a protocol of a prospective longitudinal observational study

Abstract

Introduction Neurocognitive deficits after stroke are a common manifestation and pose a significant impact on the quality of life for patients and families; however, little attention is given to the burden and associated impact of cognitive impairment following stroke. The study aims to determine the prevalence and predictors of post-stroke cognitive impairment (PSCI) among adult stroke patients admitted to tertiary hospitals in Dodoma, Tanzania Methodology A prospective longitudinal study is conducted at tertiary hospitals in the Dodoma region, central Tanzania. So far, participants with the first stroke confirmed by CT/MRI brain aged ≥ 18 years who meet the inclusion criteria are enrolled and followed up. Baseline socio-demographic and clinical factors are identified during admission, while other clinical variables are determined during the three-month follow-up period. Descriptive statistics are used to summarize data; continuous data will be reported as Mean (SD) or Median (IQR), and categorical data will be summarized using proportions and frequencies. Univariate and multivariate logistic regression analysis will be used to determine predictors of PSCI

30-day in-hospital stroke case fatality and significant risk factors in sub-Saharan–Africa: A systematic review and meta-analysis

“…A total of ten (10) significant risk factors were identified. These were low Glasgow Coma Score <8 [24,28,34,35,48,50,58,61,63,73,95,96,100,105], high (�10) National Institute Health Stroke Scale score [40,57,58,60,78,82,87,92,114], aspiration pneumonia [27,63,73,82,87,88,90,95,100,114], hemorrhagic stroke [29,40,92,95,105], brain edema/ intra-cranial pressure [28,34,88,114], hyperglycemia [35,40,50], untyped stroke (stroke diagnosis not confirmed by neuroimaging) [28,34,95], recurrent stroke [29,…”