Predictors of survival among adult Ethiopian patients in the national ART program at Seven University Teaching Hospitals: A prospective cohort study

Survival Status and Its Predictors Among Adult Human Immunodeficiency Virus Infected Patients Attending Their Antiretroviral Treatment at Health Centers in Kirkos Sub City, Addis Ababa, Ethiopia. A Retrospective Cohort Study

“…And lower than studies done in Addis Ababa, Ethiopia, the mortality incidence was 3.8/100 person-years, 3.9 per 100mperson year in Harar, Ethiopia and another higher mortality rate of 10.3%; 5.4 deaths/100 person-years was reported from a study done at seven universities based on national ART follow-up data and 3.4 deaths per 100 person-years in Dilla [10], [12]- [14]. And present study nding is higher than study ndings done in southern Ethiopia 2.03 per 100 person-years [7], eastern Ethiopia 1.89 deaths per 100 person-years [15], and study done in Uganda [16].…”

“…According to the study, most of the deaths (60%) were within the rst 6 months [15]. And another multi-site prospective cohort study done in Ethiopia also revealed that seventy percent of the deaths occurred within six months of starting ART [12]. But in some other studies, the majority of deaths occurring within three months of starting ART [12], [14], [17].…”

“…And another multi-site prospective cohort study done in Ethiopia also revealed that seventy percent of the deaths occurred within six months of starting ART [12]. But in some other studies, the majority of deaths occurring within three months of starting ART [12], [14], [17]. The reason could be the fact that usually HIV patients come to institution after advanced clinical stage and at early time, lack of drug adherence could contribute to high mortality.…”

Performance of the Antiretroviral Treatment Program in Ethiopia, 2005-2015: strengths and weaknesses toward ending AIDS

“…In Ethiopia, after 12 months on ART, only 0Á58% of patients are transitioned to second-line ART, reflecting lower levels of viral load testing. Moreover, evidence from a cohort study in seven University teaching hospitals in Ethiopia shows that 7Á3% of patients on ART failed on their first-line regimens after 12 months on ART (Fekade et al, 2017). In sub-Saharan Africa, the number of patients on second-line ART is expected to increase with the roll-out of routine viral load monitoring (Lecher et al, 2015).…”

Establishing a multicenter longitudinal clinical cohort Study in Ethiopia: Advanced Clinical Monitoring of Antiretroviral Treatment Project

“…The ACM platform enabled researchers to determine predictors of survival among adults on ART (15), common causes of hospitalization and outcomes among pediatric patients on ART (16), magnitude of drug toxicity (17), timeliness of HIV care (18) and mortality of patients on ART with TB co-infection (19). Answers to more research questions are in the pipeline and the authors anticipate many more research activities based on the data and specimens collected by ACM.…”