Predictors of treatment non-response for depression in a sample of female adolescents with risk-taking and self-injurious behavior – A one year follow-up

Vöckel, Jasper; Sigrist, Christine; Kaess, Michael; Koenig, Julian

doi:10.1016/j.jad.2022.12.073

Cited by 1 publication

(3 citation statements)

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“…A recent meta-analysis of nonresponse in ICBT reported that of the 2,118 patients, 26.8% were classified as nonresponders [ 15 ]. A better understanding of the nonresponse rate and its predictors may guide the choice or development of individualized treatment approaches, aiming to increase response rates among those affected [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

“…Since many patients are considered nonresponders, it is important to find the risk factors and determinants of this category. Evidence on nonresponse predictors has been inconsistent [ 15 , 17 ]. Several studies have identified various patient variables, such as sociodemographic, comorbidity, baseline symptom severity, adherence, and personality, as predictors of treatment outcome [ 18 – 20 ].…”

Section: Introductionmentioning

confidence: 99%

“…Several studies have identified various patient variables, such as sociodemographic, comorbidity, baseline symptom severity, adherence, and personality, as predictors of treatment outcome [ 18 – 20 ]. For example, previous studies suggested that high pre-treatment symptom severity [ 14 , 17 ] and comorbidity [ 14 ] are associated with poorer response, while other studies showed that having more symptoms, higher education, and being female were predictors of treatment improvement [ 21 , 22 ]. However, most studies focus on the responders rather than explicitly examining the nonresponders.…”

Section: Introductionmentioning

confidence: 99%

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Predictors of nonresponse to treatment and low adherence to internet-based cognitive behavioral therapy in depressed/anxious women facing the couple’s fertility problems: a secondary analysis of a randomized control trial

Shafierizi,

Basirat,

Nasiri-Amiri

et al. 2024

BMC Psychiatry

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Background The study aimed to examine the predictors of treatment nonresponse and low adherence to Internet-based cognitive behavioral therapy and face-to-face therapy for treating depression and anxiety in women facing the couple’s fertility problems. Methods This is a secondary analysis based on a previous randomized controlled trial including 152 depressed/anxious women facing the couple’s fertility problems. The study defines low adherence as receiving less than 4 sessions (out of 8 sessions). Nonresponse to treatment refers to a < 50% reduction in the anxiety and depression total scores. Results A high level of anxiety/depression score before psychotherapy increases the risk of nonresponse to both Internet-based and face-to-face psychotherapies by 1.4 to 2 times in women facing the couple’s fertility problems after the treatment and in the 6-month follow-up. However, 4 factors, including diagnosis of mixed anxiety and depression, low education level, long marriage duration, and infertility caused by mixed female/male factors, reduced the risk of nonresponse to psychotherapies. Conclusion Women facing the couple’s fertility problems with high depression and anxiety scores are at risk of poor prognosis in response to psychotherapy. Psychologists and healthcare providers of infertility centers should pay more attention to the timely identification and referral of depressed/anxious patients to psychologists.

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Section: Introductionmentioning

confidence: 99%