Predilection Role Diabetes Mellitus and Dyslipidemia in the Onset of Ischemic Stroke

Abstract

4Primary Health Care Center Ilijas, Bosnia and Herzegovina 5 I ntroduction: Stroke is the third leading cause of mortality, disability and dementia, but leading cause of epileptic manifestations in the elderly. Diabetes mellitus as permanently elevated blood glucose, often accompanied by dyslipidemia, is among the leading causes of atherosclerotic alteration in blood vessels and is also increasing in the world. Goal: To determine the existence and predilection of diabetes mellitus and dyslipidemia, in the development of ischemic stroke. Material and methods: During the 2011 are analyzed all people with stroke admitted at the Neurology Clinic. All patients underwent neurological tests and the laboratory test with special emphasis on the value of blood glucose and lipid levels, with brain CT which confirmed the existence of a stroke, EEG and internist examination. Results: During the one-year period the stroke was confirmed in 1184 patients, aged 33-81 years and 37% in the younger age group (up to 50 yrs.). There was 50.67% male and 49.33% female patients. Ischemic stroke was confirmed in 78.0% (56% with thrombotic and 22% with embolic genesis), of which the 32% was lacunar infarcts (up to 1.5 cm) and hemorrhagic in 22% (SAH in 4.8%, and intracerebral hemorrhage in 17.2%). The most frequent risk factors were hypertension 85%, then smoking in 65%, diabetes mellitus in 39.0%, in 27.38% dyslipidemia, previous stroke in 26.69%, in 23.57% arrhythmia In the baseline sample 30.06% of patients had previously diabetes mellitus and in 8.94% the diabetes was diagnosed during hospitalization, while dyslipidemia was known from earlier in 22.0% and in 5.38% cases was detected during the hospitalization. Among treated patients 79.01% survived, while 20.09% have a fatal outcome. Conclusions: Diabetes mellitus and dyslipidemia, along with hypertension and smoking are the leading risk factors for the occurrence of stroke. By timely detection and treatment can be controlled slow atherosclerotic changes in blood vessels and thus prevent stroke.

Trial of ORG 10172 in acute stroke treatment classification and associated risk factors of ischemic stroke: a prospective study from a tertiary care center in South India

“…Literature review showed hypertension as the major risk factor for stroke worldwide. 25,26 We found dyslipidemia as the major risk factor than hypertension for ischemic stroke being present in 79% of the cohort, higher than reported. 25,26 This is attributed to the life style changes and consumption of fatty foods (Biryani, ice creams, fast foods and meat products) in these region.…”

“…25,26 We found dyslipidemia as the major risk factor than hypertension for ischemic stroke being present in 79% of the cohort, higher than reported. 25,26 This is attributed to the life style changes and consumption of fatty foods (Biryani, ice creams, fast foods and meat products) in these region. Plasma lipids and lipoproteins have an influence on the risk of cerebral infarction, but the relationships between dyslipidemia and stroke have not been consistently elucidated.…”

Neurologinė Patologija Sergant 2 Tipo Cukriniu Diabetu

“…Išeminiu insultu sergantiems ligoniams CD nulemia blogą prognozę po trombolizės, o ankstyva poinsultinė glikemija yra susijusi su potrombolizinių simptominių ICK padaugėjimu [28]. Laiku diagnozavus ir gydant CD, galima kontroliuoti kraujagyslių aterosklerozinius pokyčius ir išvengti išeminio insulto [29]. Nagrinėjamos diabetinės ketoacidozės neurologinės komplikacijos vaikams: diabetinė ketoacidozė gali komplikuotis galvos smegenų edema ir išeminiu insultu [30].…”

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“…Değiştirilebilen risk faktörlerinin ortaya konulması serebrovasküler hastalıkların tedavi yaklaşımları açısından da önem kazanmaktadır (1).…”

“…Diabetes mellitus (DM), anormal glukoz metabolizmasının yol açtığı, beraberinde lipid ve protein metabolizmasında da değişikliklere neden olabilen kronik hiperglisemi ile karakterize metabolik bir bozukluktur (1). Hiperglisemi belirtileri gösteren olgularda açlık kan glukoz düzeylerinin ≥126 mg/dL (7.0 mmol) olması, Hemoglobin A1C'nin ≥%6.5 olması veya rastgele ölçülen kan glukoz düzeylerinin ≥200 mg/dL (11.1 mmol/l) olması DM tanısı için gereklidir (2).…”