Preface

Keehn, Philip M.; Rosenfeld, Stuart M.

doi:10.1016/b978-0-12-403001-5.50005-3

Cited by 12 publications

(13 citation statements)

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“…35 Several studies have examined compliance with various ASRM guidelines, 36 and two studies have evaluated risk disclosure on clinic and donor agency websites. 37 However, to our knowledge, no studies to date have examined compliance with the ASRM guidelines regarding risk disclosure in recruitment advertisements.…”

Section: Alberta Berry and Levinementioning

confidence: 99%

Risk Disclosure and the Recruitment of Oocyte Donors: Are Advertisers Telling the Full Story?

Alberta¹,

Berry²,

Levine³

2014

J. Law. Med. Ethics

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This study analyzes 435 oocyte donor recruitment advertisements to assess whether entities recruiting donors of oocytes to be used for in vitro fertilization (IVF) procedures include a disclosure of risks associated with the donation process in their advertisements. Such disclosure is required by the self-regulatory guidelines of the American Society for Reproductive Medicine (ASRM) and by law in California for advertisements placed in the state. We find very low rates of risk disclosure across entity types and regulatory regimes, although risk disclosure is more common in advertisements placed by entities subject to ASRM's self-regulatory guidelines. Advertisements placed in California are more likely to include risk disclosure, but disclosure rates are still quite low. California-based entities advertising outside the state are more likely to include risk disclosure than non-California entities, suggesting that California's law may have a modest "halo effect." Our results suggest that there is a significant ethical and policy problem with the status quo in light of the known and unknown risks of oocyte donation and the importance of risk disclosure to informed consent in the context of oocyte donation.

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Section: Alberta Berry and Levinementioning

confidence: 99%

Risk Disclosure and the Recruitment of Oocyte Donors: Are Advertisers Telling the Full Story?

Alberta¹,

Berry²,

Levine³

2014

J. Law. Med. Ethics

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“…The author assumed that possibly the benzylic substituted cyclophane 49 was produced due to the nonplanarity of the benzene ring of cyclophane [44] and the steric effect of isopropyl group of oxazoline [45]. These planar chiral N,Se-ligands were evaluated in palladium-catalyzed asymmetric allylic alkylation and the respective alkylated products 50 were obtained in 98% of yield and in good to excellent enantioselectivities (up to 93% ee), as shown in Scheme 31.…”

Section: Palladium-catalyzed Asymmetric Allylic Alkylationmentioning

confidence: 99%

Enantioselective Synthesis Mediated by Catalytic Chiral Organoselenium Compounds

Braga¹,

Lüdtke²,

Vargas³

2006

COC

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Selenium-based methods have developed rapidly over the past few years and certain features of chiral selenium-containing compounds make these reagents particularly valuable for efficient stereoselective reactions.Recent advances in stereoselective transformations involving one-pot selenenylation-deselenylation sequences, which occur using only catalytic amounts of the optically active diselenides in the synthesis of valuable building blocks will be summarized. Additionally, recent results of catalytic reactions using chiral selenides and diselenides such as the enantioselective copper catalyzed conjugate addition of organometallic reagents to enones, diorganozinc addition to aldehydes, palladium-catalyzed enantioselective allylic alkylation, among other topics will also be addressed.

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“…The author assumed that possibly the benzylic substituted cyclophane 30 was produced due to the nonplanarity of the benzene ring of cyclophane 36 and the steric effect of isopropyl group of oxazoline. 37 These planar chiral N,Se-ligands were evaluated in palladium-catalyzed asymmetric allylic alkylation and the respective alkylated products were furnished in 98% of yield and in good to excellent enantioselectivities (up to 93% ee), as shown in Scheme 22.…”

Section: Scheme 19mentioning

confidence: 99%

Catalytic Applications of Chiral Organoselenium Compounds in Asymmetric Synthesis

Braga¹,

Lüdtke²,

Vargas³

et al. 2006

Synlett

124

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Chiral selenium-containing compounds have found growing application in asymmetric catalysis over the past few years. The large majority of these ligands are derived from readily available chiral amino alcohols in a few high-yielding synthetic steps. The advantages of using these compounds are described, particularly those regarding ready accessibility, modular nature, formation of strong bonds with soft metals and more rarely with hard ones. By using an appropriate electrophilic or nucleophilic organoselenium fragment, novel chiral organoselenium catalysts or ligands were designed from chiral aziridines, oxazolines, ferrocenes, etc. High regioselectivity and enantioselectivity were achieved through the four following techniques: the enantioselective copper-catalyzed conjugate addition of organometallic reagents to enones, the diorganozinc addition to aldehydes, palladium-catalyzed enantioselective allylic alkylation and asymmetric hydrosilylation or transfer hydrogenations of ketones.

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Preface

Cited by 12 publications

References 0 publications

Risk Disclosure and the Recruitment of Oocyte Donors: Are Advertisers Telling the Full Story?

Risk Disclosure and the Recruitment of Oocyte Donors: Are Advertisers Telling the Full Story?

Enantioselective Synthesis Mediated by Catalytic Chiral Organoselenium Compounds

Catalytic Applications of Chiral Organoselenium Compounds in Asymmetric Synthesis

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