This article examines the impact of the World Trade Organization (WTO) on domestic trade policies and practices. It shows that protectionist measures, including those practiced by the United States, have been effectively challenged, and consequently restricted, due to the WTO strengthened dispute settlement procedures. I show that the new procedures affected the substantive policy outcomes by changing the political influence of competing actors. Specifically, I identify four transformations affecting the political influence of participants: the re-scaling of political authority, the judicialization of inter-state relations, the institutionalization of the international organization, and the structural internationalization of the state. Based on this case, the article offers a view of globalization as an institutional project. This view emphasizes the political dimension of the process of globalization; it suggests that this project was facilitated by transforming the institutional arrangements in place; and it identifies the contradictions inherent in it both to U.S. hegemony and to the globalization project itself.