Pregnancy and Asthma

Venkataraman, Mythili T.; Shanies, Harvey M.

doi:10.3109/02770909709067216

Cited by 17 publications

(3 citation statements)

References 24 publications

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“…We found that over 14% of women in our study reported provider-diagnosed asthma. While this is higher than previously reported2, 15, 16, it may not be inconsistent with other observations. It is known that the prevalence of asthma increased through the 1990's 3, 17, 18 and since our data are derived from 1998-2006, the increasing prevalence may account in part for our higher rates.…”

Section: Discussioncontrasting

confidence: 90%

Asthma in pregnancy and its pharmacologic treatment

Louik

Schätz

Hernández–Dı́az

et al. 2010

Annals of Allergy, Asthma & Immunology

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Section: Discussioncontrasting

confidence: 90%

Asthma in pregnancy and its pharmacologic treatment

Louik

Schätz

Hernández–Dı́az

et al. 2010

Annals of Allergy, Asthma & Immunology

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“…In the event that a cesarean section is needed, preanesthetic atropine and glycopyrrolate may provide bronchodilation, and ketamine is one of the preferred anesthetic agents. Halothane in small doses may also provide a mild bronchodilator effect (66). The use of halogenated compounds does increase the risk of uterine atony, and in cases in which postpartum hemorrhage is encountered, anesthetic gases with uterine relaxant activity should be discontinued until the uterus has contracted and the bleeding has stopped.…”

Section: Management Of Acute Asthma During Labor and Deliverymentioning

confidence: 98%

Acute asthma in pregnancy

Hanania

Belfort

2005

Critical Care Medicine

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“…In addition, I would emphasize that optimal medical practice as well as medicolegal prophylaxis demands that the patient's informed consent be obtained for the proposed management plan and that this informed consent be documented on the chart (9).…”

mentioning

confidence: 99%

Pregnancy and Asthma

Schatz

1997

Journal of Asthma

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The coexistence of asthma and pregnancy is important for both quantitative and qualitative reasons. Quantitatively, asthma is one of the most common potentially serious medical problems to complicate pregnancy. Qualitatively, the simultaneous management of two patients (mother and fetus) provides a unique challenge. The review article "Pregnancy and Asthma" by Venkataraman and Shanies in this month's Jourital (1) makes a number of very important points about the interrelationships between asthma and pregnancy and about the optimal management of the pregnant asthmatic. I would like to emphasize some of those points and expand upon others.Venkataraman and Shanies (1) review the respiratory changes that have been reported to occur during pregnancy. There are three important clinical implications of these changes. First, the hyperventilation of normal pregnancy appears to be related to the dyspnea of pregnancy, which is reported by up to 75% of normal women in their first or second trimesters (2). This dyspnea of early pregnancy, along with the dyspnea of later pregnancy apparently caused by upward pressure on the diaphragm near term, must be differentiated from dyspnea caused by asthma. However, since these nonasthmatic dyspneas of pregnancy are not associated with wheezing or cough, this differentiation is not generally difficult for physicians or patients. Second, the hyperventilation of normal pregnancy leads to a higher pO2 (mean 99-106) and a much lower pC02 (mean 26-30) in pregnant than in nonpregnant women (3). Thus, a p02 < 70 in a pregnant woman with acute asthma represents relatively more hypoxia than the same pO2 in a nonpregnant patient, and a pC02 2 35 represents respiratory failure during pregnancy. Third, the lack of changes in airway mechanics during normal pregnancy means that changes in FEVI, MMEF, or PEFR that may occur during pregnancy in an asthmatic patient are likely due to the asthma, not to pregnancy.As pointed out in the accompanying review article (l), the blood gas changes associated with acute asthma may impair fetal oxygenation. In addition, relatively small degrees of chronic hypoxia may reduce intrauterine growth (4). Thus, it is not surprising that studies of asthma during pregnancy have reported increased incidences of maternal and fetal complications, especially preeclampsia, perinatal mortality, low birth weight, and preterm infants (5). However, not all studies have reported these increased risks, and the mechanisms involved are not fully defined. Some 263 J Asthma Downloaded from informahealthcare.com by Michigan University on 11/03/14For personal use only.

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Pregnancy and Asthma

Cited by 17 publications

References 24 publications

Asthma in pregnancy and its pharmacologic treatment

Asthma in pregnancy and its pharmacologic treatment

Acute asthma in pregnancy

Pregnancy and Asthma

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