Pregnancy and infant outcome of 80 consecutive cord coagulations in complicated monochorionic multiple pregnancies

Lewi, Liesbeth; Gratacós, Eduard; Ortibus, Els; Schoubroeck, Dominique Van; Carreras, Elena; Higueras, Teresa; Perapoch, Josep; Deprest, Jan

doi:10.1016/j.ajog.2005.09.013

Cited by 198 publications

(150 citation statements)

References 24 publications

Supporting

Mentioning

126

Contrasting

Unclassified

Order By: Relevance

“…7,[10][11][12][13] In a series of 36 children, Robyr et al 11 reported one case with 'some form of developmental delay' at 18 months. Followup was obtained from a clinical evaluation by the referring paediatrician, a specification of delay was not described, and developmental tests were lacking.…”

Section: Discussionmentioning

confidence: 99%

“…Lewi et al reported some form of developmental delay in 5/67 (7.5%) survivors after selective feticide of the co-twin. 12 Four children were diagnosed with minor cognitive or motor delay with Bayley scales (2 nd edition) and one child had severe cognitive delay according to a paediatrician. In a series of six cases, Moise et al 7 reported all children were doing well at a mean age of 4 months.…”

Section: Discussionmentioning

confidence: 99%

“…Developmental delay is reported in up to 12%. 7,[10][11][12][13] However, in these studies standardised developmental tests and detailed specifications of a developmental delay were often lacking. In addition, besides evident impairments such as cerebral palsy or severe cognitive delay, more subtle impairments including behavioural difficulties require attention in order to obtain an integrated picture of the long-term outcome in surviving twins.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Long‐term neurodevelopmental outcome after selective feticide in monochorionic pregnancies

Klink

Koopman

Middeldorp

et al. 2015

BJOG

View full text Add to dashboard Cite

ObjectiveTo assess the incidence of and risk factors for adverse long‐term neurodevelopmental outcome in complicated monochorionic pregnancies treated with selective feticide at our centre between 2000 and 2011.DesignObservational cohort study.SettingNational referral centre for fetal therapy (Leiden University Medical Centre, the Netherlands).PopulationNeurodevelopmental outcome was assessed in 74 long‐term survivors.MethodsChildren, at least 2 years of age, underwent an assessment of neurologic, motor and cognitive development using standardised psychometric tests and the parents completed a behavioural questionnaire.Main outcome measuresA composite outcome termed neurodevelopmental impairment including cerebral palsy (GMFCS II‐V), cognitive and/or motor test score of <70, bilateral blindness or bilateral deafness requiring amplification.ResultsA total of 131 monochorionic pregnancies were treated with selective feticide at the Leiden University Medical Centre. Overall survival rate was 88/131 (67%). Long‐term outcome was assessed in 74/88 (84%). Neurodevelopmental impairment was detected in 5/74 [6.8%, 95% confidence interval (CI), 1.1–12.5] of survivors. Overall adverse outcome, including perinatal mortality or neurodevelopmental impairment was 48/131 (36.6%). In multivariate analysis, parental educational level was associated with cognitive test scores (regression coefficient B 3.9, 95% CI 1.8–6.0). Behavioural problems were reported in 10/69 (14.5%).ConclusionsAdverse long‐term outcome in survivor twins of complicated monochorionic pregnancies treated with selective feticide appears to be more prevalent than in the general population. Cognitive test scores were associated with parental educational level.Tweetable abstractNeurodevelopmental impairment after selective feticide was detected in 5/74 (6.8%, 95% CI 1.1–12.5) of survivors.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Long‐term neurodevelopmental outcome after selective feticide in monochorionic pregnancies

Klink

Koopman

Middeldorp

et al. 2015

BJOG

View full text Add to dashboard Cite

show abstract

“…However, had the band been located a few millimeters lower, the umbilical cord of the surviving fetus could have been occluded or even cut, leading to intrauterine demise. This mechanism could possibly explain some of the reported cases of late intrauterine fetal demise following selective cord coagulation 5 …”

Section: Fetal Abdominal Scarring Caused By the Umbilical Cord Of A Cmentioning

confidence: 94%

Prenatal sonographic features of complete covered cloacal exstrophy

Ono

Kikuchi

Takagi

et al. 2009

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

“…More invasive and higher-risk procedures such as cord coagulation, and now the more commonly carried out radio frequency ablation of the affected twin's cord, are necessary to reduce one twin without causing morbidity in it's co-twin. [5][6][7] In this issue of the Journal of Perinatology, Malhotra et al explore the problem of discordant anomalies in a twin pair. Modern prenatal diagnostics are making such scenarios more commonplace.…”

mentioning

confidence: 99%