Pregnancy and nephrotic syndrome due to renal amyloidosis

Successful Full-Term Pregnancy in Familial Mediterranean Fever Complicated with Amyloidosis: Case Report and Review of the Literature

“…Three of them [3,10,11] describe FMF amyloidosis. In one study [12] the amyloid osis is not specified and in another report amyloidosis was secondary to tuberculosis [ 13]. Table 1 summarizes the clinical and lab oratory data reported in these studies and in the present case.…”

“…Some of these patients also suffer from skin lesions and arthritis. Amyloidosis may complicate up to 2 5 % of FMF patients [ 1 ] and in these patients several kinships with autosomal dominant in heritance were reported [2], [10] et al [12] Pfanner [11] and Levin [13] uterus, tubes and ovaries was also reported [4]. During pregnancy, FMF bouts usually lessen [5,6], However, a 30% fetal wastage was reported [5].…”

Nephrotic syndrome in a young postpartum woman

“…Other rare chronic infections that have caused AA amyloidosis include liver abscess and chronic suppurative skin infections (eg, decubitus ulcer). 5,8 Thus, it is critical in this patient to recognize that although she had lived in the United States for 2 years, she still had different risk factors for disease than patients who have lived their whole lives in the United States. This patient was from Sudan, and familial Mediterranean fever could therefore be considered as a potential cause of amyloidosis.…”

“…There are rare reports of amyloidosis causing renal disease during pregnancy and the immediate postpartum period. 2,8,9 In cases of amyloidosis due to familial Mediterranean fever, worse renal dysfunction at conception was associated with deterioration during pregnancy. 9 Tuberculo-sis has increased in incidence in the United States over the last decades, associated with human immunodeficiency virus (HIV) infection and increasing immigration of people from areas where tuberculosis is endemic.…”