Pregnancy and perinatal outcomes after assisted reproduction: a comparative study

Allen, Cathy; Bowdin, Sarah; Harrison, Robert F.; Sutcliffe, Alastair; Brueton, Louise; Kirby, Gail; Kirkman-Brown, Jackson; Barrett, C.B.; Reardon, William; Maher, Eamonn R.

doi:10.1007/s11845-008-0172-9

Cited by 54 publications

(35 citation statements)

References 52 publications

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“…A large study of data obtained from three births registries in Western Australia revealed an increased incidence of congenital malformations in children born after IVF/ ICSI compared to children conceived naturally [19]. In addition, in a questionnaire-based comparative study (ART group versus the general population), singleton ART pregnancies had an increased risk of preterm delivery and low birth weight at term, but non-lethal congenital malformation rates were not increased following ART [20]. Moreover, a [1 -6] systematic review on the prevalence of birth defects in infants conceived after IVF/ ICSI versus spontaneously conceived infants had noted that two-thirds of the identified studies showed a 25% or greater increased risk of birth defects in the former group [21].…”

Section: Discussionmentioning

confidence: 99%

Congenital anomalies and other perinatal outcomes in ICSI vs. naturally conceived pregnancies: a comparative study

Al-Fifi

Al-Binali

Al-Shahrani

et al. 2009

J Assist Reprod Genet

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Section: Discussionmentioning

confidence: 99%

Congenital anomalies and other perinatal outcomes in ICSI vs. naturally conceived pregnancies: a comparative study

Al-Fifi

Al-Binali

Al-Shahrani

et al. 2009

J Assist Reprod Genet

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“…Allen et al [19], reported that singleton ART pregnancies have an increased risk of preterm delivery and low birth weight at term. Non-lethal congenital malformation rates are not increased following ART.…”

Section: Discussionmentioning

confidence: 99%

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Cakar

Yavuz

Kutlu

et al. 2018

ijmsci

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ABSTRACT:Background: We aimed to compare perinatal outcomes of intracytoplasmicsperm injection (ICSI) versus naturally (spontaneously) concieved age and parity matched group of singleton pregnants. Methods: Two hundred and sixteen singleton pregnancies aged between 18-45 years old were included in this study. Among all study group, 106 cases were ICSI pregnancies (study group) and 110 cases were spontaneously concieved singleton pregnancies (control group). Pregnancy outcome parameters were: the incidence of chronic hypertension, preeclampsia, gestational hypertension, placenta previa, placental abruption, preterm birth, intrahepatic cholestasis of pregnancy, gestational diabetes, preterm premature rupture of membranes, caesarean delivery. Results: There were no differences in terms of maternal age, BMI, gravidity, parity, gestational weeks at birth and birth weight between ICSI and spontaneously concieved pregnancy groups. Placental abruption, gestational diabetes and cesarean section rates were significantly higher in ICSI pregnancies than spontaneously conceived pregnancies (4.7% vs 0%, 21.7% vs 11.8% and 82.1% vs 68.2%, respectively). There wereno statistically significant differences in terms of chronic hypertension, preeclampsia, gestational hypertension, preterm labor, placenta previa, intrahepatic cholestasis of pregnancy, preterm and term premature rupture of the membranes. Conclusion: ICSI pregnancies have higher adverse perinatal outcomes than spontaneously conceived singleton pregnancies which were matched with age and parity. That's why ICSI pregnancies should be given a detailed counseling about the adverse perinatal outcomes and should be followed up more carefully through the pregnancy.

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“…Use of drugs to cause superovulation has caused the vast majority of the increase in the multiples. (5, [18][19][20][21].…”

Section: Fertility Drugs and Assisted Reproductivementioning

confidence: 99%

Multiple pregnancy and birth: Twins, triplets and high-order multiples. Overview

Lazarov¹,

Lazarov²,

Lazarov³

2016

TJS

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Multiple gestations are high risk pregnancies which may be complicated by prematurity,low birthweight, pre-eclampsia, anaemia, postpartum haemorrhage, intrauterine growth restriction, neonatal morbidity and high neonatal and infant mortality. There are more multiple births today in part because more women are receiving infertility treatment, which carries a risk of multiple pregnancy.They are many risk factors for multiple pregnancy such as: race, heredity, maternal age and pregnancy history as well as fertility drugs and assisted reproductive technology(ART). The frequency of twins increases with maternal age and number of pregnancies. Multiple pregnancy is more common in women who utilize fertility medications to undergo ovulation induction or superovulation. Assisted reproductive technology (ART) procedures such as in vitro fertilization (IVF) also contribute to the increase in the multiple birth rate. The risk of multiple pregnancy increases as the number of embryos transferred increases.

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Pregnancy and perinatal outcomes after assisted reproduction: a comparative study

Cited by 54 publications

References 52 publications

Congenital anomalies and other perinatal outcomes in ICSI vs. naturally conceived pregnancies: a comparative study

Congenital anomalies and other perinatal outcomes in ICSI vs. naturally conceived pregnancies: a comparative study

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Multiple pregnancy and birth: Twins, triplets and high-order multiples. Overview

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