Pregnancy associated acute leukemia: Single center experience

Successful therapy for acute myeloid leukemia in pregnancy

“…None of these have occurred in the presented patient. Available studies show that pregnancy does not have a significant impact on the course of AML compared to non-pregnant patients [10], and this was also the case in our patient.…”

Noninvasive prenatal testing detected acute myeloid leukemia in paucisymptomatic pregnant patient

“…8 Management of the disease is challenging, resulting in some late interventions. 7 In AML, knowledge of the genomic profile is important as recurrent genomic abnormalities have prognostic significance. AML with mutated NPM1 is often observed in association with normal karyotype and typically has a better outcome.…”

“…The disease presents with one of more of the following: cytopenia, fatigue, gum hemorrhages, and/or infections with fever 6 . Usually, the incidence of AML increases with age, being more common in patients >65 years 4,6 ; it is very rare and life‐threatening during pregnancy, 7 occurring once in about 75 000‐100 000 pregnancies, with an overall survival of approximately 30% 8 . Management of the disease is challenging, resulting in some late interventions 7 …”