Pregnancy associated pancreatitis revisited

Igbinosa, Osamuyimen; Poddar, Sameer; Pitchumoni, C. S.

doi:10.1016/j.clinre.2012.07.011

Cited by 52 publications

(29 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…APIP was more in the third (77.8%) trimesters as compared to first (11.1%) and (11.1%) second trimesters, which is consistent with the finding that the frequency of APIP increases as pregnancy progresses. 2 Acute pancreatitis (AP) in pregnancy is most often associated with gallstone disease or hypertriglyceridemia. 1,5,6 Gallstones are the most common cause of acute pancreatitis during pregnancy, accounting for more than 70% of cases.…”

Section: Discussionmentioning

confidence: 99%

“…1 Biliary tract diseases are the most common cause of acute pancreatitis in pregnancy, with gallstone disease being responsible for more than 70% of cases. 2 The susceptibility of gallstone formation during pregnancy is attributed to the lithogenic effect of gestation through estrogen and progesterone. More than 50% of cases in pregnancy are diagnosed in third trimester demonstrating that acute pancreatitis is more common with advancing gestational age, paralleling the frequency of gallstones in pregnancy.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Acute pancreatitis in pregnancy: 5-year experience from a multidisciplinary centre

Srikumar

Nair

Reghunath

et al. 2018

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Acute pancreatitis is rare in pregnancy, but it is associated with increased incidence of maternal and fetal mortality. It should be one of the differential diagnosis of upper abdominal pain with or without nausea or vomiting. S. amylase, lipase and ultrasound abdomen were the diagnostic methods. Conservative management is the main stay in mild cases. Severe cases have multiorgan involvement and needs multidisciplinary approach. The objectives of this study were to study the maternal and fetal outcome in pregnant women diagnosed with acute pancreatitis and to identify the risk factors for acute pancreatitis in pregnancy.Methods: Retrospective descriptive study of pregnant women diagnosed with acute pancreatitis in Amrita Institute of Medical Sciences, Kochi during the period of 5 years from January 2011 to December 2016. A proforma having patients age, parity index, gestational age, symptoms with duration, blood investigations, ultrasonography, interventions done, mode of delivery, supportive treatment, complications were developed. Fetal weight, Apgar score, fetal complications were also noted.Results: The mean gestational age of presentation was 30 weeks of pregnancy. Upper abdominal pain radiating to back, vomiting, fever was the commonest clinical presentation in majority of cases. The diagnostic methods were S.Amylase ,Lipase and Ultrasound abdomen. The mean age of the patients were 26 years and 66.7% were primigravidas in the present study. There were 4 patients in SAP and 5 in MAP groups. Complications in SAP group were ARF, ARDS, DIC, MODS, metabolic acidosis etc. SAP group had 3 maternal and 3 fetal loss.Conclusions: Severe acute pancreatitis has adverse maternal and fetal outcome due to multi organ failure and sepsis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Acute pancreatitis in pregnancy: 5-year experience from a multidisciplinary centre

Srikumar

Nair

Reghunath

et al. 2018

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

show abstract

“…La nutrition entérale est physiologique et aide à maintenir la flore intestinale [7]. En dehors d’une angiocholite associée, l’usage d´antibiotiques dans la pancréatite aiguë pour protège contre l’infection de la nécrose est controversé [2, 3]. Lorsqu’on les utilise, le choix des antibiotiques est difficile, à cause du risque tératogène.…”

Section: Discussionunclassified

“…Les calculs biliaires constituent l’étiologie la plus fréquemment rencontrée [1, 2]. Elle survient dans la plupart des cas au 3 ème trimestre de la grossesse [2, 3]. Son évolution peut mettre en jeu le pronostic vital maternel et fœtal.…”

Section: Introductionunclassified

Pancréatite aiguë sévère sur grossesse chez le noir Africain: à propos d’un cas

Lawani¹,

Kpossou²,

Noukpozounkou³

et al. 2017

Pan Afr Med J

View full text Add to dashboard Cite

La pancréatite aigue est un évènement rare pendant la grossesse. Elle est associée à une forte mortalité maternelle et fœtale. La lithiase biliaire est l’étiologie la plus fréquente, mais dans beaucoup de cas, la cause reste indéterminée. Nous rapportons ici le cas d’une patiente de 37 ans qui a présenté à 29 semaines d’aménorrhée une pancréatite aiguë révélée par une occlusion intestinale aiguë fébrile. Le diagnostic a été fait en per opératoire. Dans les suites opératoires la patiente a fait une fausse couche, puis est décédée au 8ème jour post opératoire.

show abstract

“…Acute pancreatitis (AP) during pregnancy is a rare, but life-threatening disease with an estimated incidence of approximately 3-10/10,000 [1,2]. AP can result in multiple organ dysfunction and disseminated intravascular coagulation owing to activation of the inflammatory and coagulation systems.…”

Section: Introductionmentioning

confidence: 99%

Role of mean platelet volume in hypertriglyceridemia-induced acute pancreatitis during pregnancy

Zeng

Cai

Chen

et al. 2019

Preprint

View full text Add to dashboard Cite

PurposeHypertriglyceridemia-induced acute pancreatitis (HTG-AP) during pregnancy is a rare but severe disease with high maternal-fetal mortality risk, which constitutes a systemic inflammatory process accompanied by thrombosis and bleeding disorders. However, the role of mean platelet volume (MPV) in HTG-AP during pregnancy remains unclear. This study aimed to assess the role of MPV and the potential relationship with disease severity in HTG-AP during pregnancy. MethodsIn the retrospective study, we collected 45 patients with HTG-AP during pregnancy as the HTG-AP group and 49 pregnant females with hypertriglyceridemia as the control group. MPV and other relevant variables at onset and remission were collected and compared. ResultsMPV levels were significantly higher in the HTG-AP group than in the control group (P < 0.001), and lower in remission than on onset (P = 0.002). According to the severity of acute pancreatitis, all subjects were classified into mild AP (MAP), moderately severe AP (MSAP), and severe AP (SAP) groups. There was a significant difference in MPV on onset among the three groups (P = 0.048), and the SAP patients had the highest levels of MPV. In addition, only in the SAP group, MPV was lower in remission than on onset (P = 0.010). ConclusionThese results may indicate an important role of MPV in evaluating the severity of HTG-AP during pregnancy. BackgroundAcute pancreatitis (AP) during pregnancy is a rare, but life-threatening disease with an estimated incidence of approximately 3-10/10,000 [1,2]. AP can result in multiple organ dysfunction and disseminated intravascular coagulation owing to activation of the inflammatory and coagulation systems. Moreover, pregnancy-related physiologic alterations influence the diagnosis and management of many diseases. Therefore, AP in pregnancy can severely affect the mother and fetus

show abstract

Pregnancy associated pancreatitis revisited

Cited by 52 publications

References 16 publications

Acute pancreatitis in pregnancy: 5-year experience from a multidisciplinary centre

Acute pancreatitis in pregnancy: 5-year experience from a multidisciplinary centre

Pancréatite aiguë sévère sur grossesse chez le noir Africain: à propos d’un cas

Role of mean platelet volume in hypertriglyceridemia-induced acute pancreatitis during pregnancy

Contact Info

Product

Resources

About