Pregnancy Complications and Neonatal Outcomes in Women With Eating Disorders

Franko, Debra L.; Blais, Mark A.; Becker, Anne E.; Delinsky, Sherrie S.; Greenwood, Dara N.; Flores, Andrea; Ekeblad, Elizabeth R.; Eddy, Kamryn T.; Herzog, David B.

doi:10.1176/appi.ajp.158.9.1461

Cited by 217 publications

(133 citation statements)

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“…Yet, clinical data suggest that many women with eating disorders are becoming mothers. [1][2][3][4] Consequently, pregnancy and motherhood have become the focus of increased attention among eating disorder researchers.…”

Section: Introductionmentioning

confidence: 99%

Associations among postpartum depression, eating disorders, and perfectionism in a population‐based sample of adult women

Mazzeo

Landt²,

Jones

et al. 2006

Intl J Eating Disorders

102

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Objective: The current study investigated associations among eating disorders, depressive symptoms during pregnancy and postpartum, and perfectionism in a population-based sample of women.Method: Females who reported !1 pregnancy (N ¼ 1,119) completed questionnaires assessing perfectionism, eating disorder symptomatology, and depression during pregnancy and postpartum. Information regarding participants' history of major depressive disorder (MDD) was also available from structured psychiatric interviews completed during a previous wave of data collection.Results: Depressive symptoms during pregnancy and postpartum were high among women with a history of eating disorders. Both binge eating disorder (BED) and bulimia nervosa (BN) were positively associated with symptoms of postpartum depression (PPD), even when lifetime MDD was controlled. However, logistic regression indicated that women with a history of BN and BED are at particular risk of developing PPD symptomatology. Linear regression analyses conducted with the subset of the sample who endorsed a PPD screening item suggested that the severity of PPD symptomatology may be attributable to Concern Over Mistakes, a specific aspect of perfectionism. Conclusion:These results highlight the importance of assessing specific features of perfectionism. In addition, they suggest that women with BN, BED, or high Concern over Mistakes may be at particular risk of developing PPD symptoms, and could benefit from prenatal screening. V V C 2006 by Wiley Periodicals, Inc.

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Section: Introductionmentioning

confidence: 99%

Associations among postpartum depression, eating disorders, and perfectionism in a population‐based sample of adult women

Mazzeo

Landt²,

Jones

et al. 2006

Intl J Eating Disorders

102

View full text Add to dashboard Cite

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“…11,41 Moreover, perinatal complications associated with a lifetime ED diagnosis include an increased risk for hyperemesis, 13,42 smoking during pregnancy, 43 lower birth weight, and birth defects such as cleft palate and neural tube defects, microcephaly, preterm delivery, and cesarean delivery. 12,16,40,[44][45][46][47] Trauma and abuse history in eating disorders and perinatal depression Women with lifetime histories of EDs are also more likely to report a history of childhood sexual abuse and physical abuse compared with women with no ED history. 48,49 Although both childhood sexual abuse [50][51][52][53][54][55] and physical abuse 49,56,57 occur in individuals with EDs, they are best viewed as nonspecific risk factors for the development of psychopathology.…”

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confidence: 99%

Eating Disorders and Trauma History in Women with Perinatal Depression

Meltzer‐Brody

Zerwas

Leserman

et al. 2011

Journal of Women's Health

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Objective: Although the prevalence of perinatal depression (depression occurring during pregnancy and postpartum) is 10%, little is known about psychiatric comorbidity in these women. We examined the prevalence of comorbid eating disorders (ED) and trauma history in women with perinatal depression. Methods: A research questionnaire was administered to 158 consecutive patients seen in a perinatal psychiatry clinic during pregnancy (n = 99) or postpartum (n = 59). Measures included Structured Clinical Interview for DSM (SCID) IV-based questions for lifetime eating psychopathology and assessments of comorbid psychiatric illness including the State/Trait Anxiety Inventory (STAI), Patient Health Questionnaire (PHQ-9), Edinburgh Postnatal Depression Scale (EPDS), and Trauma Inventory. Results: In this cohort, 37.1% reported a putative lifetime ED history; 10.1% reported anorexia nervosa (AN), 10.1% reported bulimia nervosa (BN), 10.1% reported ED not otherwise specified-purging subtype (EDNOS-P), and 7.0% reported binge eating disorder (BED). Women with BN reported more severe depression (EPDS score, 19.1, standard deviation [SD 4.3], p = 0.02; PHQ-severity 14.5, SD 7.4, p = 0.02) than the referent group of women with perinatal depression and no ED history (EPDS 13.3, SD = 6.1; PHQ 9.0, SD = 6.2). Women with AN were more likely to report sexual trauma history than the referent group (62.5% vs. 29.3%, p < 0.05), and those with BN were more likely report physical (50.0%, p < 0.05) and sexual (66.7%, p < 0.05) trauma histories. Conclusions: ED histories were present in over one third of admissions to a perinatal psychiatry clinic. Women with BN reported more severe depression and histories of physical and sexual trauma. Screening for histories of eating psychopathology is important in women with perinatal depression.

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“…Increased complications from conception through the postpartum period have been described that adversely impact maternal and fetal well-being. Maternal complications that have been noted to occur at a higher prevalence in women with AN include miscarriages and cesarean deliveries (Bulik et al, 1999, Franko et al, 2001). High cesarean rates have also been reported in women with bulimia nervosa (BN) (Mitchell et al, 1991).…”

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confidence: 99%