Pregnancy Counseling in a Young Woman With Left Ventricular Non-Compaction

Abstract

Left ventricular noncompaction (LVNC) is an uncommon form of cardiomyopathy. Its prevalence in adults is 1:5000. In the differential diagnosis of congestive heart failure, it is rarely the etiology. The etiology of LVNC may be genetic or acquired. There are not guidelines regarding pregnancy planning or outcome in women with this disease. In this presentation, we bring the issue of genetics and pregnancy counseling in women with left ventricular noncompaction.

Pregnancy Complicated by Non-Compaction Cardiomyopathy in the Mother and Fetus: A Case Report of Both Maternal Management and Prenatal Diagnosis

“…Patient reported symptoms should prompt investigation and cardiac function should be assessed routinely throughout pregnancy. Given the paucity of data to guide anticoagulation management, our approach includes initiation of low-dose (81-162 mg) aspirin and reserve prophylactic anticoagulation for depressed ejection fraction (< 35%) or atrial fibrillation which is well supported by the literature [1,8]. Antenatal testing, serial obstetric ultrasound imaging and fetal echocardiograms should be included as part of the routine management for patients affected by LVNC.…”

“…cardiomyopathy attributed to failure of ventricular compaction during embryogenesis [1,2]. It is characterized by a prominent trabecular meshwork and deep intra-trabecular myocardial crypts located principally near the apex of either or both ventricles which extend in communication with the ventricular cavity.…”

“…Typically, the left ventricle is dilated and demonstrates a reduction in its contractile potential [2]. LVNC is estimated to occur in 1:5000 adults [1]. Clinical symptoms can include heart failure, arrhythmia, and thromboembolism [4].…”