Pregnancy in kidney recipients under cyclosporine

Abstract

About 1 of every 50 women of child-bearing age who have a functioning kidney transplant become pregnant. Successful pregnancies following kidney allotransplantation with conventional immunosuppressive treatment are well described [8), and there is no evidence of abnormalities in the infants born. The use of cyclosporine (CSA) means new problems for the pregnant women and the fetus: the risk of congenital abnormalities, fetal growth retardation, hepato-and nephrotoxicity.We report the experience of 16 pregnancies in 16 of our kidney transplant patients, of which 7 were treated with CSA.