Pregnancy in primary biliary cirrhosis

Wong, Kok-Kien; Goh, Khean‐Lee

doi:10.1016/0028-2243(92)90232-n

Cited by 18 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was especially evident in the earlier series of Whelton and Sherlock 5 , where all four pregnancies that progressed to the third trimester were complicated by worsening jaundice. Two other studies did not find deterioration of liver function during pregnancy 7,8 . Only two studies reported treatment of primary biliary cirrhosis in pregnancy 9,11 .…”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

Pregnancy in primary biliary cirrhosis complicated by portal hypertension: report of a case and review of the literature

Goh

Gull

Alexander

2001

BJOG

View full text Add to dashboard Cite

a Case reportA 39 year old woman came to the antenatal clinic for booking at the 12 th week of her ®fth pregnancy. She complained of pruritis, particularly over her hands and feet. The pruritis preceded her pregnancy by ®ve months. There was no change in urine or stool colour and her appetite was good. Physical examination showed no abnormality. She had no rash, took no medication, and there was no family history of liver disease. She drank less than 15 units of alcohol per week before her pregnancy and had then become abstinent.She had four previous pregnancies, the ®rst pregnancy being complicated by pre-eclampsia at term, the second and third ending in miscarriages in the ®rst trimester, and the fourth being an uneventful full term pregnancy. Five years previously she had attended her general practitioner with tiredness, nausea, headache, reduced appetite and her stool looking`different'. Liver function tests revealed an elevated gamma-glutamyl transferase level at 112 iu/L. Ultrasound examination of her liver was normal. Liver function tests repeated one week later showed no change. As her symptoms had improved by the second consultation, no follow up was thought necessary. Her past medical history included infection with hepatitis A virus, and depression after her second miscarriage.

show abstract

Section: Discussionmentioning

confidence: 95%

“…Only 14 cases of pregnancy occurring in women with primary biliary cirrhosis have been reported in the English literature 3,5–10. Six women had marked deterioration of liver function 5,9 .…”

Section: Discussionmentioning

confidence: 99%

Pregnancy in primary biliary cirrhosis complicated by portal hypertension: report of a case and review of the literature

Goh

Gull

Alexander

2001

BJOG

View full text Add to dashboard Cite

show abstract

“…This was especially evident in the earlier series of Whelton and Sherlock 5 , where all four pregnancies that progressed to the third trimester were complicated by worsening jaundice. Two other studies did not ®nd deterioration of liver function during pregnancy 7,8 . Only two studies reported treatment of primary biliary cirrhosis in pregnancy 9,11 .…”

Section: Discussionmentioning

confidence: 96%

Pregnancy in primary biliary cirrhosis complicated by portal hypertension: report of a case and review of the literature

Goh

Gull

Alexander

2001

British Journal of Obstetrics and Gynaecology

View full text Add to dashboard Cite

Case reportA 39 year old woman came to the antenatal clinic for booking at the 12 th week of her ®fth pregnancy. She complained of pruritis, particularly over her hands and feet. The pruritis preceded her pregnancy by ®ve months. There was no change in urine or stool colour and her appetite was good. Physical examination showed no abnormality. She had no rash, took no medication, and there was no family history of liver disease. She drank less than 15 units of alcohol per week before her pregnancy and had then become abstinent.She had four previous pregnancies, the ®rst pregnancy being complicated by pre-eclampsia at term, the second and third ending in miscarriages in the ®rst trimester, and the fourth being an uneventful full term pregnancy. Five years previously she had attended her general practitioner with tiredness, nausea, headache, reduced appetite and her stool looking`different'. Liver function tests revealed an elevated gamma-glutamyl transferase level at 112 iu/L. Ultrasound examination of her liver was normal. Liver function tests repeated one week later showed no change. As her symptoms had improved by the second consultation, no follow up was thought necessary. Her past medical history included infection with hepatitis A virus, and depression after her second miscarriage.

show abstract

“…Although the reasons for the different outcomes in AIH patients during and after pregnancy are not clear at present, we assume that they are related to differential variations in complex hormonal profiles between individuals. Similarly, exacerbations of PBC during pregnancy were also reported in addition to improvement and stability of PBC during pregnancy (27,28).…”

Section: Discussionmentioning

confidence: 86%

Flare-up of Autoimmune Hepatitis After Delivery in a Patient with Primary Biliary Cirrhosis: Postpartum Overlap Syndrome of Primary Biliary Cirrhosis and Autoimmune Hepatitis

et al. 2005

View full text Add to dashboard Cite

Pregnancy in primary biliary cirrhosis

Cited by 18 publications

References 6 publications

Pregnancy in primary biliary cirrhosis complicated by portal hypertension: report of a case and review of the literature

Pregnancy in primary biliary cirrhosis complicated by portal hypertension: report of a case and review of the literature

Pregnancy in primary biliary cirrhosis complicated by portal hypertension: report of a case and review of the literature

Flare-up of Autoimmune Hepatitis After Delivery in a Patient with Primary Biliary Cirrhosis: Postpartum Overlap Syndrome of Primary Biliary Cirrhosis and Autoimmune Hepatitis

Contact Info

Product

Resources

About