Pregnancy in women with Klippel-Trenaunay syndrome: Report of three pregnancies in a single patient and review of literature

Abstract

Klippel-Trenaunay syndrome is characterised by vascular abnormality which increases the risk of thromboembolism and haemorrhage. Physiological changes in pregnancy pose an increased risk to these complications. Being an uncommon disorder, there is limited literature about the management of women with pregnancy and Klippel-Trenaunay syndrome. We report in detail two of three pregnancies in a woman with Klippel-Trenaunay syndrome who had repeated episodes of haematochezia leading to anaemia, managed with Argon laser Photo-Coagulation in pregnancy and also reviewed the complications and the management of pregnant women with Klippel-Trenaunay syndrome.

Pregnancy management for a woman with extensive vulvar and pelvic malformations caused by Klippel–Trénaunay syndrome

“…Most case reports of pregnancy in KTS patients indicate that radiological imaging prior to the expected delivery date provides crucial information about the extent of the syndrome and any vascular malformations. 8 , 11 , 12 , 13 , 14 Consequently, we carried out a preoperative MRI. Although aggravation of KTS symptoms in pregnancy is well‐documented, our patient's symptom level remained constant.…”

“…Most case reports of pregnancy in KTS patients indicate that radiological imaging prior to the expected delivery date provides crucial information about the extent of the syndrome and any vascular malformations 8,11–14 . Consequently, we carried out a preoperative MRI.…”