Pregnancy outcome after elective cervical cerclage in relation to type of suture material used

Israfil‐Bayli, Fidan; Toozs‐Hobson, Philip; Lees, C.; Slack, Mark; Ismail, Khaled

doi:10.1016/j.mehy.2013.04.003

Cited by 21 publications

(12 citation statements)

References 14 publications

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“…However, the spaces between the suture strands provide an optimal environment for bacteria to multiply and protect the bacteria by preventing the larger natural immune macrophages from reaching them, which thereby increases the risk of infection [37,38]. In contrast, non-braided suture types exhibit less tissue reactivity and a reduced chance of infection due to the very smooth surface characteristics of single filaments [39]. It has been hypothesised that cerclage disruption might contribute to cervical stenosis, second trimester miscarriage and preterm delivery [17,40].…”

Section: Discussionmentioning

confidence: 99%

Incidence, risk factors and treatment of cervical stenosis after radical trachelectomy: A systematic review

Jin

2015

European Journal of Cancer

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Section: Discussionmentioning

confidence: 99%

Incidence, risk factors and treatment of cervical stenosis after radical trachelectomy: A systematic review

Jin

2015

European Journal of Cancer

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“…Mersilene ® ) u otra, la que suele infectarse y mantener la infección. La cinta multifilamento usada en mujeres embarazadas con riesgo de infección aumenta la posibilidad de resultado adverso por esta causa 78 . Debe hacerse en el primer trimestre y no esperar el acortamiento cervical ya que el aumento de citoquinas pro-inflamatorias existente en el flujo cérvicovaginal de estas pacientes, aumenta el riesgo de aborto de segundo trimestre y de PP 26 .…”

Section: Cerclaje Profiláctico En Pacientes Con Antecedente De Abortounclassified

¿Se puede prevenir el parto prematuro por infección bacteriana ascendente y sus resultados adversos en los hospitales públicos de Chile?

Ovalle

Martínez

Figueroa

2019

Rev. chil. infectol.

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Can preterm birth be prevented from ascending bacterial infection and its adverse results in the public hospitals of Chile?Preterm birth (PB) is the main contributor to the perinatal morbidity/mortality. In spite of the knowledge of the risk factors and the introduction of medical interventions intended to prevent PB, its frequency has increased. Ascending bacterial infection (ABI) is the obstetric condition most frequently associated to PB causing an important adverse perinatal outcome in a public hospital in Chile. This review shows the association between PB and ABI, analyzes the physiopathology and immunology of vaginal infections in the susceptible pregnant woman., as well as their application in this group of effective measures demonstrated by evidence, such as routine control, treatment of genitourinary tract infections (GTI), prophylactic or therapeutic cerclage, use of probiotics, use of vaginal progesterone, metabolic control of diabetes mellitus and weight of the obese woman. Treatment GTI together with the use of medical interventions that improve the vaginal immunity in the risk population allow to predict a reduction of PB by ABI and of its immediate consequences, long term sequels and high associated costs, with the consequent benefit of the public health in Chile.

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“…We subsequently conducted a systematic review, which identified only two non-randomised studies (NRS). The NRS meta-analysis demonstrated that non-braided cervical suture is associated with a significant risk reduction in pregnancy loss compared to multifilament/braided sutures (odds ratio =0.24; 95% confidence interval 0.06 to 0.96) [6]. …”

Section: Introductionmentioning

confidence: 99%

Cerclage outcome by the type of suture material (COTS): study protocol for a pilot and feasibility randomised controlled trial

Israfil‐Bayli

Toozs‐Hobson

Lees

et al. 2014

Trials

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BackgroundCervical incompetence is one of the causes of preterm birth and mid-trimester pregnancy loss. Cervical cerclage is a surgical procedure to treat cervical incompetence. Cervical cerclage reduces the incidence of preterm birth in women at risk of recurrent preterm birth, without a statistically significant reduction in perinatal mortality or neonatal morbidity. Multifilament/braided sutures such as Mersilene tape have been traditionally used for cervical cerclage. Braided sutures, particularly mesh-like non-absorbable sutures, have been associated with an increased risk of infection and, hence, some obstetricians prefer to use monofilament/non-braided sutures. However, these claims are not substantiated by any scientific or clinical evidence.We propose a pilot/feasibility study which will provide the necessary information for planning a definitive trial investigating the clinical effectiveness of monofilament non-braided suture materials in reducing pregnancy loss rate following cervical cerclage compared to the traditional multifilament braided sutures.Methods/DesignWomen eligible for elective or ultrasound-indicated cerclage at 12 to 21 + 6 weeks of gestation will be randomised to having the procedure using either a monofilament non-braided suture (Ethilon) or a Multifilament braided suture (Mersilene tape) inserted using a McDonald technique. Consent for participation in the Cerclage outcome by the type of suture (COTS) study will be obtained from each eligible participant.Clinical trials registrationCOTS is registered with the International Standard Research for Clinical Trials (ISRCTN17866773). Registered on 27 March 2013.

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Pregnancy outcome after elective cervical cerclage in relation to type of suture material used

Cited by 21 publications

References 14 publications

Incidence, risk factors and treatment of cervical stenosis after radical trachelectomy: A systematic review

Incidence, risk factors and treatment of cervical stenosis after radical trachelectomy: A systematic review

¿Se puede prevenir el parto prematuro por infección bacteriana ascendente y sus resultados adversos en los hospitales públicos de Chile?

Cerclage outcome by the type of suture material (COTS): study protocol for a pilot and feasibility randomised controlled trial

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