2018
DOI: 10.5897/ijnm2018.0305
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Pregnancy outcome and early postnatal weights in diabetic and non-diabetic pregnant rats administered ethanolic extract of Ocimum gratissimum leaves during pregnancy

Abstract: Extract of Ocimum gratissimum (OG), also known as scent leaf, is popularly used to treat diabetes mellitus and its hypoglycaemic activity has been confirmed by in vivo studies. The aim was to investigate the effect of this extract on placenta development and birth outcome in diabetic pregnancy. Forty two pregnant rats weighing 150-200 g were used. They were divided into control and extract treated diabetic and non-diabetic groups with 6 rats in each subgroup. Extract treated groups were administered 200 and 40… Show more

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“…For example, Vernonia amygdalina leaves (VAL) and Ocimum gratissimum leaves (OGL) are commonly used to manage sickle cell disease (SCD) [ 2 ]. The leaves are macerated in an aqueous or alcoholic medium, and the extracted juice is administered [ 3 , 4 ]. Vernonia amygdalina , commonly known as “bitter leaf,” is a small shrub with dark green leaves and rough bark [ 5 ], mainly growing in tropical Africa but domesticated in many parts of West Africa.…”
Section: Introductionmentioning
confidence: 99%
“…For example, Vernonia amygdalina leaves (VAL) and Ocimum gratissimum leaves (OGL) are commonly used to manage sickle cell disease (SCD) [ 2 ]. The leaves are macerated in an aqueous or alcoholic medium, and the extracted juice is administered [ 3 , 4 ]. Vernonia amygdalina , commonly known as “bitter leaf,” is a small shrub with dark green leaves and rough bark [ 5 ], mainly growing in tropical Africa but domesticated in many parts of West Africa.…”
Section: Introductionmentioning
confidence: 99%