Pregnancy Outcome Following Mustard Procedure for Transposition of the Great Arteries

Megerian, Garo; Bell, Joseph G.; Huhta, James C.; Bottalico, Joseph N.; Weiner, Stuart

doi:10.1097/00006250-199404000-00005

Cited by 25 publications

(18 citation statements)

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“…In case reports and small series of up to 11 pregnancies (13)(14)(15)(16)(17)(18)(19)(20)(21) looking at the outcome of pregnancy in asymptomatic or mildly symptomatic women after an intra-atrial baffle repair, the authors have described symptomatic heart failure requiring therapy during pregnancy (13,14,16,17,19 -21), deterioration in RV systolic function (13,14,16,19,20), development of supraventricular arrhythmias (13,14,18,21), stroke (21), and death (20,21). These results, like our data, confirm that pregnancy after a Mustard operation can be successful but carries a risk of deterioration in functional class, even in women who are asymptomatic before pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Impact of pregnancy on the systemic right ventricle after a Mustard operation for transposition of the great arteries

Guédès

Mercier

Leduc

et al. 2004

Journal of the American College of Cardiology

163

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Section: Discussionmentioning

confidence: 99%

Impact of pregnancy on the systemic right ventricle after a Mustard operation for transposition of the great arteries

Guédès

Mercier

Leduc

et al. 2004

Journal of the American College of Cardiology

163

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“…Data relating to the outcome of pregnancy in these women are limited to several medium-sized case series, [15][16][17][18][19] a number of smaller series and case reports. [20][21][22][23][24][25] All are retrospective. Due to the rarity of the condition, there are no single-centre series; all are either multi-centre or based on retrospective analyses of National Registries.…”

Section: Introductionmentioning

confidence: 99%

Pregnancy following Mustard or Senning correction of transposition of the great arteries: a retrospective study

Cataldo

Doohan²,

Rice

et al. 2015

BJOG

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Objective To determine pregnancy outcome in women with atrial switch repair for transposition of the great arteries (TGA) and to compare follow up with a control group of childless women with the same repair.Design Retrospective cohort study.Setting Tertiary care medical centre.Population About 21 patients compared with 15 controls.Methods Review of records from joint cardiac-obstetric clinic 1993-2013.Main outcome measures Occurrence of cardiovascular events: maternal death, heart failure, arrhythmia, thromboembolic events, worsening systemic ventricular function, worsening tricuspid valve regurgitation and newly detected baffle problems.Results There were 34 pregnancies in 21 women. Mean follow up was 100 months. No deaths or recurrence occurred. Events (few arrhythmias, thromboembolic events and baffle issues) were common in both groups: 13 (62%) patients and eight (53%) controls (P = 0.736). Worsening of ventricular function was similar in both groups: six (29%) patients and four (27%) controls (P = 0.899). Worsening tricuspid regurgitation was more common in patients [11 (52%)] than controls (0)] (P < 0.001). Labour was induced in 76% cases: 32% for cardiac deterioration, 37% to control timing of delivery, and 26% for intrauterine growth restriction. Delivery was vaginal in 84% cases. Median gestational age was 37 (30-40) weeks, median birthweight 2525 g (1460-3530). In all, 38% babies were premature and 38% were small-for-gestational-age.Conclusions Cardiac events after atrial repair for TGA are equally common in pregnant women and non-pregnant controls, although worsening tricuspid regurgitation occurs more frequently in pregnancy. Induction of labour is to be expected but vaginal delivery is achievable in most cases. Infants are likely to be premature and small-for-gestational-age.Keywords Atrial repair pregnancy, congenital heart disease, transposition of the great arteries.Tweetable abstract Pregnancy in atrial repair for TGA: cardiac events similar to controls, prematurity and small babies likely.

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“…In 1910, Lewis published a landmark treatise on AF and established the term auricular fibrillation, which he defined as "a condition in which normal impulse formation in the auricle is replaced by stimulus production at multiple auricular foci. Co-ordinate contraction is lost; the normal and regular impulses transmitted to the ventricle are absent, while rapid and haphazard impulses produced in the auricle take their place and produces gross irregularity of the ventricular action" (140).…”

Section: Atrial Fibrillationmentioning

confidence: 99%

Management of Cardiac Arrhythmias

Mb¹

2011

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Pregnancy Outcome Following Mustard Procedure for Transposition of the Great Arteries

Abstract: If a patient with transposition of the great arteries who underwent the Mustard procedure is hemodynamically stable before pregnancy, good maternal and fetal outcome can be expected.

Cited by 25 publications

References 0 publications

Impact of pregnancy on the systemic right ventricle after a Mustard operation for transposition of the great arteries

Impact of pregnancy on the systemic right ventricle after a Mustard operation for transposition of the great arteries

Pregnancy following Mustard or Senning correction of transposition of the great arteries: a retrospective study

Management of Cardiac Arrhythmias

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