Pregnancy Outcome in Gestational Diabetes Mellitus-A Prospective Observational Study

Ramalingam, K.; Devisrimurari,; Bollu, Mounica.; Ali, Shaik Faizan

doi:10.5958/2394-2754.2015.00003.x

Cited by 2 publications

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“…In the study of Ramalingam et al also age >25 years was the common risk associated with GDM following by past history of fetal loss. 11,12 In our study also age appears to be the dominant risk factor (88.3%) as is in par with that of Dixon et al 8 Despite the earlier tradition and customs of early marriages and teenage pregnancies, still in some parts of India the higher percentage of GDM women with age >25 years can be due to change in social trends. Presently in India women are educating themselves gaining employment and building their carrier which inevitably delay the age of marriage and pregnancy The second most common risk factor is found to be obesity as per the study of Dixon DRD et al this risk was seen in 47% whereas in our study the corresponding figure is 58.1%.…”

Section: Discussionsupporting

confidence: 74%

Gestational diabetes mellitus-universal versus selective screening

Hymavathi

Tadisetti

Polisetty

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONDiabetes mellitus is a metabolic disorder characterised by hyperglycaemia resulting from defects in Insulin secretion, action or both. Several distinct types of diabetes mellitus exist and are caused by a complex interaction of genetic, environmental factors and life style choices. 1 The prevalence of diabetes mellitus in India, is found to be 2.4% in rural and 4-11.6% in urban population. High frequencies of impaired glucose tolerance ranging from 3.6-9.1% indicate the potential for further rise in prevalence of diabetes mellitus in the coming decades.2 Normal pregnancy is associated with altered maternal glucose homeostasis and metabolism. It is important to identify a pregnant woman with GDM because of its association with significant metabolic alterations, increased perinatal and maternal morbidity and mortality leading to long term morbidity among the mothers and their off spring. 3 The frequency of GDM and the associated morbidity emphasises the importance of an appropriate screening method. The screening of all pregnant women for GDM universally recommended in the second and third international workshops on GDM and the WHO expert committee on diabetes but the Fourth international workshop conference on GDM including American college of obstetricians and gynaecologists (ACOG) emphasised on selective screening. [4][5][6] Is it possible to use selective screening based ABSTRACT Background:The prevalence of diabetes mellitus is increasing globally and Indian population is found to be ethnically in high risk group. Gestational diabetes mellitus (GDM) offers a unique and valuable opportunity for the development and implementation of clinical strategies for future prevention of diabetes. There is immense need for optimal screening strategies to spot out women with gestational diabetes. Methods: Prospective case study.1000 pregnant women were recruited into the study at an early gestational age (<20 weeks). They were broadly divided into two groups A (without risk factors) and B (with risk factors).The whole study population (both A and B) is subjected to oral glucose challenge test (OGCT) with the concept of Universal screening. Those with abnormal OGCT are subjected to Oral glucose tolerance test (OGTT).Women with abnormal GTT values are designated as having GDM. The results are analyzed. Results: 11.7% in group A and 25.4% in group B were found to have abnormal OGCT values and when they were subjected to OGTT 44.2% in group A and 45.8% in group B are detected to have abnormal OGTT values. 87.9% of GDM women were found to be in the age group 21-25 years in group A and in group B (59.5%) were of >26 years. labor outcome by caesarean section in GDM cases was up to 60% and 51.3% being elective sections. On the whole neonatal outcome was satisfactory. Conclusions: As Indian population are ethnically more prone for diabetes, there is immense need to adopt universal screening for GDM in pregnancy. Thus, a timely action can be taken as depicted in the present study by screening all pregnant women, irrespe...

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Section: Discussionsupporting

confidence: 74%

Gestational diabetes mellitus-universal versus selective screening

Hymavathi

Tadisetti

Polisetty

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…The family history of Diabetes for women was same (8.3%) in the Case and Control groups respectively, which is slightly lower (11.26%) than in cases of diabetes from Ramalingam et al [11]. According to Kumari et al's [7] findings, 22.4% of diabetic women and 10.5% of non-diabetic women (p=0.02) had a family history of diabetes.…”

Section: Discussionmentioning

confidence: 69%

“…Among the Case group, multigravida (61.2%) predominates over primigravida (36%) and grand multigravida (2.8%). Ramalingam et al [11] has shown similarities as they reported 29.5% of primigravida and 69.01% of multigravida.…”

Section: Discussionmentioning

confidence: 88%

“…The mean birth weight was found to be 2.84±0.67 kgs for the neonates born to the Case group. The Ramalingam et al [11] study reports that only 14% of babies born over 4 kg indicate macrosomia and 68.11% of babies born between 2.6 and 3.9 kg. According to our research, 25% of babies born to the Case group weigh less than 2.4 kg, 75% weigh between 2.4 and 4 kg, and there were no newborns with macrosomia.…”

Section: Discussionmentioning

confidence: 99%

“…There is a lack of information regarding the results of treatment-controlled diabetes in pregnancy, despite the fact that numerous studies on the subject have been conducted throughout India, including those by Mahalakshmi et al [6] in Chennai, Seshiah et al [9] in Chennai, K Ramalingam et al [11] in Guntur and Manni Mohan raj Mahalakshmi et al [12] in Chennai. In order to reinforce the importance of maintaining glycaemic control during pregnancy, our study attempts to determine the impact of diabetes on pregnancy outcomes.…”

Section: The International Association Of Diabetes Pregnancy Study Gr...mentioning

confidence: 99%

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Pregnancy Outcomes in Diabetic Mothers with Controlled Glycemia: A Case-Control Study

Reddy,

Charitha,

Jannabhatla

et al. 2024

JAMPS

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Background: Overt Diabetes mellitus and Gestational diabetes mellitus (GDM) can complicate pregnancy. Early detection and management of the disease should be done to ensure better maternal and foetal outcomes. Our goal is to compare treatment-controlled diabetic women with non-diabetic women to evaluate the pregnancy-related unfavourable outcomes. Methods and Materials: This is a single-centre case-control study with women, from Nellore, Andhra Pradesh, who gave birth between September 2022 and February 2023. A total of 144 patients, including 72 women with diabetes and controlled glycemia (case group, n=72), were compared with non-diabetic women (control group, n=72). Various pregnancy-related outcomes were observed. The student t-test and SPSS were used for statistical analysis to compare Results: Average ages were 24±4.9 years and 27.83±6.24 years in controls and cases, respectively. Mean pregnancy duration was 268.15±7.1 days in controls and 257.1±31.2 days in cases. The cases had a mean HbA1C of 6.05%, indicating controlled levels. Caesarean births were observed in 75% of cases and 51.3% of controls. While macrosomia (>4 kg) was not observed, 25% of cases had low birth weight (<2.5 kg). Family history, gravidity, consanguinity, newborn sex, APGAR score, nuchal cord, asphyxia, and need for respiratory support did not significantly differ between the cases and controls. However, there was a significant difference (p<0.05) in the gestation period, previous neonatal loss, type of previous deliveries, caesarean delivery, baby weight, hyperbilirubinemia, and present neonatal loss between diabetic mothers and non-diabetic mothers. Conclusion: A well-managed chronic hyperglycaemia was thought to prevent multiple pregnancy-related problems for both the mother and the baby. This study aimed to investigate this point. Though many complications were avoided with controlled glycemia in our study, complications such as caesarean deliveries, preterm births, low birth weight, hyperbilirubinemia, and neonatal loss were more prevalent in cases. This highlights the need for further research, especially in understanding and possibly intensifying glycaemic goals for diabetic mothers.

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Pregnancy Outcome in Gestational Diabetes Mellitus-A Prospective Observational Study

Cited by 2 publications

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Gestational diabetes mellitus-universal versus selective screening

Gestational diabetes mellitus-universal versus selective screening

Pregnancy Outcomes in Diabetic Mothers with Controlled Glycemia: A Case-Control Study

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