Pregnancy outcome with Marfan's syndrome and aortic root replacement

Singh, Pushpendra; Jha, Rani; Caplin, JL; Masson, E. A.; Russell, I.F.; Lindow, S. W.

doi:10.1080/01443610801916106

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Aortic Dissection1

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Cited by 3 publications

(1 citation statement)

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“…European guidelines advise against pregnancy with root diameters above 40 mm [23]. Risks may be reduced by prepregnancy elective aortic root replacement and may therefore be recommended in patients with root enlargement above 45 mm [24][25][26].…”

Section: Aortic Dissectionmentioning

confidence: 99%

Cardiac disease in pregnancy

Curry

Swan

Steer

2009

Current Opinion in Obstetrics &Amp; Gynecology

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Section: Aortic Dissectionmentioning

confidence: 99%

Cardiac disease in pregnancy

Curry

Swan

Steer

2009

Current Opinion in Obstetrics &Amp; Gynecology

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Abnormalities of Dermal Fibrous and Elastic Tissue

2011

Andrews' Diseases of the Skin

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Severe heart disease complicating pregnancy does not preclude a favourable pregnancy outcome: 15 years’ experience in a single centre

Michaelson‐Cohen

Elstein

Ioscovich

et al. 2011

Journal of Obstetrics and Gynaecology

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Heart disease (HD) in pregnancy remains a major cause of non-obstetric maternal and neonatal mortality and morbidity. This study describes the outcome in 164 pregnant women with HD (158 deliveries in women in New York Heart Association (NYHA) Classes 1 and 2; 17 in NYHA Classes 3 and 4) who received good antenatal care and benefitted from a specific protocol and experience of a dedicated staff. There were no maternal or neonatal deaths; 46 women were diagnosed peripartum. Based on a sub-division into NYHA categories, and when sub-divided by HD, there were no statistically significant differences between groups with regard to maternal age, gestational age at admission or at delivery, birth weight, 5 min Apgar scores, mode of delivery (caesarean delivery), senior obstetric/anaesthesiology staff in attendance or delivery during day/working hours. There was a higher incidence of pre-term deliveries in women with rheumatic heart disease and Marfan syndrome (p = 0.06) relative to others. Babies of women with coronary heart disease had prolonged postpartum course in the NICU (p = 0.0001) and longer total hospital stays for the mother. In conclusion, well-managed, motivated mothers with HD who benefit from comprehensive antenatal care, and are managed primarily by their obstetric and anaesthesia teams, can aspire to a good outcome for themselves and their babies.

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Pregnancy outcome with Marfan's syndrome and aortic root replacement

Cited by 3 publications

References 7 publications

Cardiac disease in pregnancy

Cardiac disease in pregnancy

Abnormalities of Dermal Fibrous and Elastic Tissue

Severe heart disease complicating pregnancy does not preclude a favourable pregnancy outcome: 15 years’ experience in a single centre

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