Pregnancy outcomes following different types of bariatric surgery: A national cohort study

Cornthwaite, Katie; Prajapati, Chetan; Lenguerrand, Erik; Knight, Marian; Blencowe, Natalie S; Johnson, Andrew B.; Draycott, Timothy; Siassakos, Dimitrios

doi:10.1016/j.ejogrb.2021.02.031

Cited by 20 publications

(11 citation statements)

References 31 publications

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“…Additionally, the different surgical bariatric procedures used were comparable to Heusschen et al [21]. This is important for comparison since a study showed that pregnancy outcomes after a bariatric procedure might vary among the different bariatric procedures [27]. In short, the most important finding of this study was that the surgery-to-delivery interval had no impact on the health outcomes for the offspring in the first year of life.…”

Section: Discussionmentioning

confidence: 55%

The Timing of Pregnancies After Bariatric Surgery has No Impact on Children’s Health—a Nationwide Population-based Registry Analysis

et al. 2022

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Purpose Bariatric surgery has a favorable effect on fertility in women. However, due to a lack of data regarding children’s outcomes, the ideal time for conception following bariatric surgery is unknown. Current guidelines advise avoiding pregnancy during the initial weight loss phase (12–24 months after surgery) as there may be potential risks to offspring. Thus, we aimed to analyze health outcomes in children born to mothers who had undergone bariatric surgery. The surgery-to-delivery interval was studied. Materials and Methods A nationwide registry belonging to the Austrian health insurance funds and containing health-related data claims was searched. Data for all women who had bariatric surgery in Austria between 01/2010 and 12/2018 were analyzed. A total of 1057 women gave birth to 1369 children. The offspring’s data were analyzed for medical health claims based on International Classification of Diseases (ICD) codes and number of days hospitalized. Three different surgery-to-delivery intervals were assessed: 12, 18, and 24 months. Results Overall, 421 deliveries (31%) were observed in the first 2 years after surgery. Of these, 70 births (5%) occurred within 12 months after surgery. The median time from surgery to delivery was 34 months. Overall, there were no differences noted in frequency of hospitalization and diagnoses leading to hospitalization in the first year of life, regardless of the surgery-to-delivery interval. Conclusion Pregnancies in the first 24 months after bariatric surgery were common. Importantly, the surgery-to-delivery interval had no significant impact on the health outcome of the children. Graphical Abstract

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Section: Discussionmentioning

confidence: 55%

The Timing of Pregnancies After Bariatric Surgery has No Impact on Children’s Health—a Nationwide Population-based Registry Analysis

et al. 2022

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“…Although the positive impact of BS on various pregnancy outcomes has been well-established, there is a major concern that BS may increase some risks, in particular IUGR and PTD [11,22]. International studies published so far have reported discordant results and the majority have small sample size and heterogeneous study designs and methodologies [10][11][12][13][14][15].…”

Section: Discussionmentioning

confidence: 99%

“…Although the number of pregnancies after BS has rapidly increased over the past years and several population-based studies have assessed the impact of BS on perinatal outcomes, the findings of these studies remain controversial [10][11][12][13][14][15]. Recent studies suggested that BS in women with severe obesity may improve both fertility and perinatal outcomes and, specifically, reduce the risks for GDM, preeclampsia, and macrosomia, compared with pregnant obese women who have not undergone BS [16][17][18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Pregnancy and post-partum outcomes of obese women after bariatric surgery: A case-control study

Savastano¹,

Caruso²,

Pompeo

et al. 2022

European Journal of Obstetrics & Gynecology and Reproductiv

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“…The risk for surgical complications was lower for pregnancies after gastric banding in comparison with gastric bypass and sleeve. Birthweight was higher for new-borns after gastric banding in comparison with gastric bypass [ 56 ]. In a large study performed in the USA, the LABS-2 study, weight loss after a bariatric intervention was not decreased with a subsequent pregnancy, while prepregnancy surgical intervention (laparoscopic adjustable gastric banding and Roux-en‑Y gastric bypass) was not associated with differences in offspring birth weight [ 57 ].…”

Section: Bariatric Surgery and Obesitymentioning

confidence: 99%

Reproductive outcomes after bariatric surgery in women

Micić

Toplak

Mićić

et al. 2021

Wien Klin Wochenschr

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SummaryThe presence of obesity may significantly influence female fertility through various mechanisms. Impairment of the hypothalamic-pituitary-ovarian axis in obese women may induce anovulation and infertility. Obesity may have an effect on women’s spontaneous and assisted conception rates, increased miscarriage rates, premature labor, stillbirth and perinatal risks, and menstrual irregularity. It has been suggested that weight loss improves reproductive outcomes due to fertility amelioration and an improvement in menstrual irregularity and ovulation. It is still not known which weight reduction procedures (changes in lifestyle, pharmacological management or bariatric intervention) result in optimal outcome on infertility. Currently, bariatric surgery is defined as the best available method for the management of obesity and its associated diseases.We have analyzed literature facts about effects of bariatric surgery on the function of the hypothalamic-pituitary-ovarian axis, polycystic ovary syndrome (PCOS), anti-Mullerian hormone (AMH) and sexual dysfunction in obesity and pregnancy in obesity. Immediate positive effects of bariatric surgery are evident at the moment, while for long-term outcomes more prolonged follow-up investigations should be done.

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Pregnancy outcomes following different types of bariatric surgery: A national cohort study

Cited by 20 publications

References 31 publications

The Timing of Pregnancies After Bariatric Surgery has No Impact on Children’s Health—a Nationwide Population-based Registry Analysis

The Timing of Pregnancies After Bariatric Surgery has No Impact on Children’s Health—a Nationwide Population-based Registry Analysis

Pregnancy and post-partum outcomes of obese women after bariatric surgery: A case-control study

Reproductive outcomes after bariatric surgery in women

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