Pregnancy outcomes following in vitro fertilization treatment in women with previous recurrent ectopic pregnancy

Xue, Yamei; Zhang, Haocheng

doi:10.1371/journal.pone.0272949

Cited by 5 publications

(1 citation statement)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With the improvement of IVF technique and IVF treatment affordability, the role of ART in EP population becomes increasingly significant.. The study conducted by Yamei Xue et al found there was no difference in pregnancy rate, live birth rate, miscarriage rate and ectopic rate in IVF patients regarding of EP history [18]. Same result was found, He Cai et al revealed no statistically difference in live birth rate and recurrent EP rate comparing patient with EP, intrauterine pregnancy or never had conceived [19].…”

Section: Discussionmentioning

confidence: 99%

Long-Term Follow Up of Fecundability after Ectopic Pregnancy in Taiwan: A Nationwide Population-Based Study

Yin,

Lee,

Chang

et al. 2024

Preprint

View full text Add to dashboard Cite

(1) Background: Ectopic pregnancy (EP) is when fertilized ovum implanted outside of uterine cavity. The incidence was 1.5% to 2.0% of all pregnancies [1, 2]. EP decreases fertility ability [3]. This study focused on the pregnancy rate after EP and various parameters influencing pregnancy. (2) Methods: The data was extracted from National Health Insurance Research Database (NHIRD) during 2000-2013. The study group enrolled women with one EP history. Those who did not have EP was put into the control group. Chi-square/Fisher exact test was performed on category variable and t-test was used on continue variables. (3) Results: The EP group had a higher cumulative rate of conceive, 41.55% than control group, 37.14% and 1.16 times higher risk in developing pregnancy (P&lt;0.001). The conceiving rate was lower than the control group in the first 5 years, but higher than the control group in the 10th to 14th years. (4) Conclusions: The fecundability after EP is lower at the beginning, but regained after long term follow.

show abstract

Section: Discussionmentioning

confidence: 99%

Long-Term Follow Up of Fecundability after Ectopic Pregnancy in Taiwan: A Nationwide Population-Based Study

Yin,

Lee,

Chang

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Is it necessary to perform a routine hysteroscopy before first embryo transfer in patients with previous ectopic pregnancy history: A propensity score matching analysis?

Xiao,

Liao,

Lin

et al. 2024

Preprint

View full text Add to dashboard Cite

Purpose To determine whether an office hysteroscopy is required before the first embryo transfer in infertile women with previous ectopic pregnancy history. Methods Consecutive patients with previous ectopic pregnancy history were categorized into two groups based on the performance of hysteroscopy. Subgroup 1 consisted of patients whose endometrial pathology was normal, subgroup 2 who were diagnosed with endometrial polyps (EP), and subgroup 3 diagnosed with chronic endometritis (CE). Demographics, baselines of characteristics, and pregnancy outcomes after embryo transfer were compared among these groups. Results A total of 614 patients were enrolled. No differences were observed in the baseline characteristics of these groups. The clinical pregnancy rates were comparable between hysteroscopy group and non-hysteroscopy group. The spontaneous miscarriage rate was greater in the cured CE subgroup compared to the normal and EP subgroups. Consequently, the live birth rate was comparatively lower in the cured CE group than in both the control group and the EP group. Conclusions We found a high pregnancy loss rate in women with CE-confirmed immunohistochemically. While office hysteroscopy serves as a valuable diagnostic instrument, it is imperative that it be supplemented with appropriate and adequate antibiotic therapy. Further investigation is still required before it can be considered a standard infertile workup before the first embryo transfer in patients with previous ectopic pregnancy history. Trial registration N/A.

show abstract

Ectopic Pregnancy History as an Independent Factor Associated with Recurring Ectopic Pregnancy in Women with Bilateral Salpingectomies. A Matched-Pair Study of IVF Patients

Lin,

Xu,

Liang

et al. 2024

Clin. Exp. Obstet. Gynecol.

View full text Add to dashboard Cite

Background: The incidence of ectopic pregnancy (EP) is purportedly elevated among individuals with a history of EP (referred to as the EP group) compared to those with no previous ectopic pregnancy (non-EP group). Nevertheless, the question of whether an EP history represents an autonomous risk factor for subsequent ectopic pregnancy of in vitro fertilization-embryo transfer (IVF-ET) patients remains a subject of debate. Methods: This study is a retrospective cohort study conducted at a single center. A total of sixty-seven patients with a prior ectopic pregnancy (EP) who underwent bilateral salpingectomy were included, and they were age-matched with a control group of 201 patients who did not have a history of EP but underwent bilateral salpingectomy during the period from January 2011 to April 2017. In all cases, laparoscopic salpingectomy was performed, followed by subsequent IVF-ET and frozen-thawed embryo transfer (FET) cycles. Results: The cumulative clinical pregnancy rates in the EP group and non-EP group were 65.7% and 73.6%, respectively, demonstrating no significant difference. Likewise, the cumulative live birth rates between the two groups were comparable (50.7% in the EP group vs. 63.6% in the non-EP group, p = 0.2). However, the incidence of ectopic pregnancy was significantly higher in the EP group compared to the non-EP group (15.9% vs. 3.4%, p = 0.003). Subsequent regression analyses revealed a significant association between a history of EP and an elevated risk of ectopic pregnancy. Conclusions: Women with a history of ectopic pregnancy even if they have had bilateral salpingectomies are at a significantly higher risk of subsequent ectopic pregnancies, indicating that a prior ectopic pregnancy is an independent risk factor for this condition, even if fallopian tubes have been removed.

show abstract

Pregnancy outcomes following in vitro fertilization treatment in women with previous recurrent ectopic pregnancy

Cited by 5 publications

References 38 publications

Long-Term Follow Up of Fecundability after Ectopic Pregnancy in Taiwan: A Nationwide Population-Based Study

Long-Term Follow Up of Fecundability after Ectopic Pregnancy in Taiwan: A Nationwide Population-Based Study

Is it necessary to perform a routine hysteroscopy before first embryo transfer in patients with previous ectopic pregnancy history: A propensity score matching analysis?

Ectopic Pregnancy History as an Independent Factor Associated with Recurring Ectopic Pregnancy in Women with Bilateral Salpingectomies. A Matched-Pair Study of IVF Patients

Contact Info

Product

Resources

About