2022
DOI: 10.1182/blood-2022-159681
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Pregnancy Surveillance in Sickle Cell Disease Patients: A Cohort Study in an African Country - Angola

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“…Nigeria, Ghana, and DRC have a sickle cell trait prevalence between 20% and 30% while some parts of Uganda have a prevalence as high as 45% ( Regional Committee for Africa, 2006 ). Angola has a SCD prevalence rate of approximately 2% ( Brito et al ., 2022 ). Gabon has an estimated SCD prevalence rate of 1.8% ( Minto’o et al ., 2022 ) and Cameroon has an estimated prevalence rate of 0.6% ( Alima Yanda et al ., 2017 ).…”
Section: Methodsmentioning
confidence: 99%
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“…Nigeria, Ghana, and DRC have a sickle cell trait prevalence between 20% and 30% while some parts of Uganda have a prevalence as high as 45% ( Regional Committee for Africa, 2006 ). Angola has a SCD prevalence rate of approximately 2% ( Brito et al ., 2022 ). Gabon has an estimated SCD prevalence rate of 1.8% ( Minto’o et al ., 2022 ) and Cameroon has an estimated prevalence rate of 0.6% ( Alima Yanda et al ., 2017 ).…”
Section: Methodsmentioning
confidence: 99%
“…Prevalence estimates of sickle cell trait for Cameroon, Democratic Republic of Congo (DRC), Gabon, Ghana and Nigeria are between 20% and 30% but in Uganda are estimated up to 45% ( Regional Committee for Africa, 2006 ). In Angola, the prevalence of SCD is about 2%, with sickle cell carriers reaching 21% of the population ( Brito et al ., 2022 ). Recent estimates for Tanzania found a disease prevalence of 1.2% and trait prevalence of 20.3% using blood spot samples from children born to mothers with human immunodeficiency virus ( Ambrose et al ., 2020 ), however this is likely to be an underestimate due to sub-optimal screening.…”
Section: Introductionmentioning
confidence: 99%