Prehypertension and mortality in a nationally representative cohort

Prehypertension in disease-free adults: a marker for an adverse cardiometabolic risk profile

“…Relative risk for PreHTN when compared with normal BP was higher (all-cause HR 1.27, 95% CI: 1.02-1.58); CVD mortality HR 1.66, 95% CI: 1.21-2.26) in NHANES II (1976)(1977)(1978)(1979)(1980). 22 These differences were, however, negated when adjustments for CVD risk factors were instituted. 22 In a subsequent study with NHANES III (follow-up through 2000) compared with normotension, the relative risks of CVD mortality for PreHTN were 1.23 (95% CI: 0.85-1.79, P¼0.26).…”

“…22 These differences were, however, negated when adjustments for CVD risk factors were instituted. 22 In a subsequent study with NHANES III (follow-up through 2000) compared with normotension, the relative risks of CVD mortality for PreHTN were 1.23 (95% CI: 0.85-1.79, P¼0.26). 23 Table 2 Estimated weighted prevalence (s.e.)…”

Prehypertension: A necessity !!!

“…It is accepted that Lifestyle modifications are an important and accepted modality of treatment for DISEASES like Diabetes, Obesity and Hypertension, but in a Prehypertensive patient, without any vascular high-risk condition the efficacy of lifestyle modification has not been proved by any formal studies so far. The results of few studies are to the contrary [2].…”

“…The letter dwells on the "fashioning" of a new category termed prehypertension" including individuals with BP 120-139 and /or 80-89 mm Hg by JNC VII [2].…”

“…JNC VII states that prehypertension is NOT a disease category, rather it defines a group of individuals who have a higher risk of developing hypertension and/or complications thereof and will benefit from follow up and intervention and hence may more appropriately be termed "at risk" category [2].…”