Prehypertension, the Risk of Hypertension and Events

Abstract

Highlights• Prehypertension is a precursor of hypertension in a high proportion of individuals. • Several factors may predispose to the development of prehypertension including uric acid, dietary salt intake, arterial stiffness, autonomic imbalance, obesity, and subclinical inflammation. • Progression of prehypertension to hypertension has been associated with visceral abdominal fat, sympathetic overactivity, sympathovagal imbalance, endothelial dysfunction, impairment of coronary flow reserve, and metabolic syndrome. Age, gender, ethnicity, and baseline blood pressure may also affect the incidence of hypertension. • Prehypertension is associated with increased risk for coronary heart disease, stroke, chronic kidney disease, and cardiovascular death, but not all-cause mortality. • Lifestyle measures and antihypertensive drugs may delay or even prevent the progression of prehypertension to hypertension.

Analysis of Hypertension in Peru: Prevalence, Associated Factors, Knowledge, Management and Control, 2014-2022

“…Recognizing prehypertension as a risk state for developing HTN is vital for implementing preventive strategies. Despite changes in terminology, focusing on prehypertension underscores the importance of early detection and intervention to prevent progression to HTN (21)(22)(23) . On the other hand, ABP offers a more dynamic assessment of blood pressure, allowing for early identification of those at risk (24,25) .…”