Background: The management of facial defects has rapidly changed in the last decade. Functional and esthetic requirements have steadily increased along with the refinements of surgery.Methods: To achieve excellence, a comprehensive spectrum of osteoplastic surgical methods, in particular in combination with each other, is required to meet this challenge. Osteomyocutaneous flaps, advanced block grafting techniques, especially complex prefabricated composite grafts, and distraction osteogenesis last being the most recent surgical method both in reconstructive and orthognathic face surgery, are in use.Results: Since osseous deficiencies of any kind ranging from aging, malocclusion-related skeletal disfigurement to orofacial defects result in facial deformities and impairment of function, the goal of osteoplastic surgery is the reconstruction of the skeletal architecture to achieve an esthetic and functional musculoskeletal balance of the face. Exemplary are CLP and the complete clinical picture of facial aging.Conclusions: Against this background plastic-reconstructive face surgery, craniofacial surgery and oral implant surgery still exist in isolated clinical fields although an interdisciplinary approach on new surgical concepts would be able to shift the border of the possible considerably.Because of the complexity of the demonstrated osteoplastic proceedings, oral surgery and its used bone substituted materials will only be marginally reviewed.