Preliminary analysis of the pandemic H1N1 influenza on Réunion Island (Indian Ocean): surveillance trends (July to mid-September 2009)

Thouillot, F.; Do, Catherine; Balleydier, Elsa; Rachou, Emmanuelle; Staïkowsky, F.; Morbidelli, P.; Jacques-Antoine, Yves; Bourdé, A.; Lagrange-Xélot, Marie; Poubeau, P.; Winer, Arnaud; Gaüzère, Bernard-Alex; Michault, Alain; Jaffar‐Bandjee, Marie‐Christine; Henrion, G.; Filleul, Laurent; D’Ortenzio, Éric

doi:10.2807/ese.14.42.19364-en

Cited by 8 publications

(21 citation statements)

References 2 publications

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“…Also, PCR assays were published very quickly [9]–[11], so that diagnostic expertise was distributed further. However, especially during the early phase of pandemic virus circulation, a co-circulation of the seasonal influenza A (and B) viruses has to be expected, and indeed was observed on the southern hemisphere from spring to fall 2009 [12]–[15]. Therefore, precise diagnostics including subtype determination are important for a comprehensive epidemiological surveillance.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Approach for the Differentiation of the Pandemic Influenza A(H1N1)v Virus from Recent Human Influenza Viruses by Real-Time PCR

et al. 2010

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BackgroundThe current spread of pandemic influenza A(H1N1)v virus necessitates an intensified surveillance of influenza virus infections worldwide. So far, in many laboratories routine diagnostics were limited to generic influenza virus detection only. To provide interested laboratories with real-time PCR assays for type and subtype identification, we present a bundle of PCR assays with which any human influenza A and B virus can be easily identified, including assays for the detection of the pandemic A(H1N1)v virus.Principal FindingsThe assays show optimal performance characteristics in their validation on plasmids containing the respective assay target sequences. All assays have furthermore been applied to several thousand clinical samples since 2007 (assays for seasonal influenza) and April 2009 (pandemic influenza assays), respectively, and showed excellent results also on clinical material.ConclusionsWe consider the presented assays to be well suited for the detection and subtyping of circulating influenza viruses.

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Section: Discussionmentioning

confidence: 99%

Diagnostic Approach for the Differentiation of the Pandemic Influenza A(H1N1)v Virus from Recent Human Influenza Viruses by Real-Time PCR

et al. 2010

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“…Le virus grippal est également connu pour son tropisme neurologique pouvant donner des convulsions et des encé-phalites surtout chez l'enfant [17][18][19], ce que nous avons retrouvé dans cette étude.…”

Section: Discussionunclassified

“…Les premiers cas ont été constatés en juillet 2009 chez des patients ayant séjourné en Australie [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]. L'épidémie a rapidement progressé touchant les adultes et les enfants, ces derniers étant plus fréquemment touchés par le virus de la grippe quel que soit le sérotype [13].…”

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Étude clinique d’une cohorte de 94 enfants atteints de la grippe A(H1N1)v à l’île de La Réunion

Bue

Chevallier

Kherchiche

2011

Bull. Soc. Pathol. Exot.

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We conducted a monocentric retrospective study at the Félix-Guyon Regional Hospital, Saint-Denis, Réunion Island, from August 1, 2009 to September 30, 2009. We included 94 children with nasal and/or throat swabs tested positive for influenza A(H1N1)v during the study period. We describe the clinical, biological, and radiological presentations, the hospitalization rate, and the antiviral and antibiotic therapies. Children between six months and two years were the ones most at risk of severe forms and the first risk factor was asthma. Children with risk factors were at risk of severe forms except immune suppressed children. 7% of our cohort had only digestive signs. Recommendations for antiviral treatment were followed in 75% of the treated children. Risk factors and clinical signs, not age, guided physicians in the initiation of treatment.

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“…The weekly activity data for ILI reported by sentinel physicians and the results of virological tests allowed estimating the number of incident cases of influenza A (H1N1) pdm09 having occurred on the island every week (Fig. 4) [16].…”

Section: Impact Of the Network On Exceptional Outbreaksmentioning

confidence: 99%

Sentinel physician's network in Reunion Island: A tool for infectious diseases surveillance

Brottet

Jaffar‐Bandjee²,

Rachou³

et al. 2015

Médecine et Maladies Infectieuses

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Preliminary analysis of the pandemic H1N1 influenza on Réunion Island (Indian Ocean): surveillance trends (July to mid-September 2009)

Cited by 8 publications

References 2 publications

Diagnostic Approach for the Differentiation of the Pandemic Influenza A(H1N1)v Virus from Recent Human Influenza Viruses by Real-Time PCR

Diagnostic Approach for the Differentiation of the Pandemic Influenza A(H1N1)v Virus from Recent Human Influenza Viruses by Real-Time PCR

Étude clinique d’une cohorte de 94 enfants atteints de la grippe A(H1N1)v à l’île de La Réunion

Sentinel physician's network in Reunion Island: A tool for infectious diseases surveillance

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