In this paper the analysis and description of the operation of the Premix station for dosing the substrate into existing digesters whose location is in the system of the device for processing of liquid waste are described. Apart from the capacity and other entry parameters, the necessary diameter of the pipeline with the length of the section for supplying the devices of the PreMix system is calculated, as it is given in the appropriate tables, the connection of the existing equipment and digesters is presented. The appropriate dependence of the volume flow, the velocity of circulation and power at constant pressure as well as the dependence of the volume flow, pressure and power at constant velocity of circulation are presented by diagrams.